| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 34 | 34 | 13 | 18 | 4.95 | .314 | 1.37 | 9.4 | 3.0 | 8.4 | 223.2 | 232 | 130 | 123 | 31 | 74 | 208 | 1 | 0 | 0 | 0 | 17 | 1 | 6 | 3.95 |
| SP | Brown, M.Brown, Mordecai # >> | 32 | 1908 | R | 85 | 32 | 32 | 11 | 13 | 5.08 | .307 | 1.30 | 8.9 | 2.8 | 3.8 | 221.2 | 219 | 132 | 125 | 21 | 69 | 93 | 8 | 0 | 0 | 1 | 16 | 6 | 4 | 4.41 |
| SP | Gooden, D.Gooden, Dwight # >> | 21 | 1985 | R | 68 | 32 | 32 | 12 | 14 | 5.12 | .318 | 1.39 | 9.9 | 2.7 | 6.3 | 232.0 | 254 | 136 | 132 | 38 | 69 | 163 | 11 | 0 | 0 | 2 | 15 | 2 | 8 | 4.64 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 30 | 30 | 11 | 14 | 4.93 | .314 | 1.35 | 8.9 | 3.3 | 6.7 | 211.2 | 208 | 118 | 116 | 35 | 78 | 158 | 6 | 0 | 0 | 3 | 13 | 4 | 5 | 4.82 |
| RP | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 86 | 0 | 6 | 5 | 3.87 | .310 | 1.33 | 8.3 | 3.7 | 7.8 | 130.1 | 120 | 56 | 56 | 16 | 53 | 112 | 0 | 11 | 3 | 0 | 0 | 3 | 0 | 4.17 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 62 | 0 | 3 | 2 | 3.47 | .293 | 1.23 | 6.4 | 4.6 | 8.1 | 70.0 | 50 | 27 | 27 | 7 | 36 | 63 | 0 | 6 | 4 | 0 | 0 | 1 | 0 | 4.09 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 46 | 0 | 1 | 3 | 4.96 | .328 | 1.46 | 8.8 | 4.5 | 6.9 | 52.2 | 51 | 31 | 29 | 7 | 26 | 40 | 0 | 4 | 0 | 0 | 0 | 0 | 3 | 4.71 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 60 | 45 | 0 | 2 | 1 | 2.78 | .271 | 1.10 | 6.8 | 3.1 | 7.8 | 58.1 | 44 | 21 | 18 | 12 | 20 | 50 | 0 | 1 | 2 | 0 | 0 | 1 | 1 | 5.05 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 2 | 2 | 0 | 2 | 11.91 | .460 | 2.56 | 18.0 | 5.7 | 4.1 | 11.1 | 22 | 15 | 15 | 1 | 7 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.18 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 1 | 0 | 0 | 0 | 0.00 | .000 | 0.00 | 0.0 | 0.0 | 9.0 | 1.2 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.00 |
| SP | Russell, R.Russell, Reb >> | 27 | 1916 | L | 53 | 26 | 0 | 3 | 4 | 5.31 | .343 | 1.54 | 11.3 | 2.5 | 3.5 | 39.0 | 49 | 25 | 23 | 8 | 11 | 15 | 0 | 3 | 0 | 0 | 0 | 1 | 1 | 5.82 |