| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 8 | 8 | 3 | 4 | 5.17 | .293 | 1.20 | 7.8 | 3.0 | 7.3 | 54.0 | 47 | 31 | 31 | 8 | 18 | 44 | 4 | 0 | 0 | 1 | 4 | 2 | 2 | 4.41 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 8 | 8 | 3 | 1 | 4.86 | .309 | 1.32 | 9.8 | 2.2 | 8.7 | 53.2 | 58 | 32 | 29 | 8 | 13 | 51 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 3.83 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 68 | 7 | 7 | 0 | 5 | 8.50 | .383 | 1.83 | 13.0 | 3.5 | 6.3 | 36.0 | 52 | 34 | 34 | 11 | 14 | 25 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 6.83 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 23 | 0 | 2 | 1 | 3.99 | .253 | 1.02 | 6.4 | 2.8 | 8.5 | 38.1 | 27 | 19 | 17 | 5 | 12 | 36 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 3.76 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 19 | 0 | 2 | 1 | 1.44 | .176 | 0.64 | 4.3 | 1.4 | 8.3 | 25.0 | 12 | 4 | 4 | 2 | 4 | 23 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 2.68 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 56 | 10 | 0 | 1 | 1 | 5.84 | .373 | 1.78 | 12.0 | 4.5 | 5.3 | 12.1 | 16 | 8 | 8 | 0 | 6 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.33 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 58 | 1 | 0 | 1 | 0 | 0.00 | .000 | 0.00 | 0.0 | 0.0 | 9.0 | 1.1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.00 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 48 | 4 | 0 | 1 | 0 | 4.15 | .381 | 1.73 | 10.1 | 6.8 | 12.4 | 8.2 | 9 | 4 | 4 | 0 | 6 | 11 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 2.88 |