| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 31 | 31 | 9 | 15 | 3.97 | .288 | 1.19 | 7.7 | 3.0 | 6.5 | 204.0 | 175 | 94 | 90 | 25 | 68 | 148 | 4 | 0 | 0 | 1 | 21 | 5 | 5 | 4.22 |
| SP | Hendrix, C.Hendrix, Claude # >> | 25 | 1914 | R | 69 | 30 | 30 | 12 | 14 | 3.75 | .280 | 1.13 | 7.5 | 2.7 | 4.5 | 208.2 | 174 | 90 | 87 | 23 | 62 | 103 | 11 | 0 | 0 | 3 | 17 | 7 | 2 | 4.44 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 30 | 30 | 8 | 16 | 4.66 | .306 | 1.28 | 9.3 | 2.3 | 8.2 | 181.2 | 187 | 100 | 94 | 32 | 46 | 164 | 5 | 0 | 0 | 0 | 14 | 7 | 2 | 4.36 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 30 | 30 | 4 | 13 | 5.35 | .330 | 1.44 | 9.9 | 3.1 | 4.2 | 166.2 | 183 | 101 | 99 | 25 | 57 | 78 | 0 | 0 | 0 | 0 | 13 | 6 | 1 | 5.16 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 28 | 28 | 3 | 16 | 6.46 | .329 | 1.45 | 10.6 | 2.5 | 5.3 | 154.2 | 182 | 117 | 111 | 34 | 43 | 91 | 5 | 0 | 0 | 0 | 7 | 2 | 4 | 5.56 |
| RP | Bailey, A.Bailey, Andrew # >> | 25 | 2009 | R | 67 | 70 | 0 | 7 | 6 | 5.61 | .343 | 1.55 | 8.7 | 5.4 | 9.2 | 78.2 | 75 | 50 | 49 | 13 | 47 | 80 | 0 | 4 | 5 | 0 | 0 | 1 | 5 | 4.96 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 59 | 54 | 0 | 2 | 5 | 4.13 | .336 | 1.46 | 8.0 | 5.3 | 9.0 | 56.2 | 50 | 28 | 26 | 8 | 33 | 56 | 0 | 1 | 0 | 0 | 0 | 3 | 3 | 4.79 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2010 | R | 50 | 49 | 0 | 3 | 2 | 2.99 | .268 | 1.08 | 6.9 | 2.9 | 5.3 | 69.1 | 53 | 23 | 23 | 6 | 22 | 41 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 3.94 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 50 | 8 | 0 | 0 | 0 | 9.37 | .380 | 1.84 | 14.6 | 2.3 | 13.5 | 16.1 | 26 | 17 | 17 | 4 | 4 | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.00 |