| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 31 | 31 | 15 | 11 | 2.88 | .267 | 1.07 | 7.2 | 2.5 | 6.0 | 256.2 | 204 | 88 | 82 | 29 | 71 | 171 | 13 | 0 | 0 | 2 | 21 | 5 | 1 | 4.03 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 30 | 30 | 13 | 14 | 4.77 | .322 | 1.41 | 9.6 | 3.1 | 5.5 | 213.0 | 227 | 116 | 113 | 31 | 73 | 130 | 5 | 0 | 0 | 0 | 14 | 4 | 5 | 4.76 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 30 | 30 | 10 | 17 | 4.10 | .301 | 1.28 | 9.2 | 2.3 | 5.1 | 239.0 | 243 | 118 | 109 | 26 | 62 | 136 | 10 | 0 | 0 | 1 | 16 | 4 | 9 | 4.10 |
| SP | Hudson, D.Hudson, Daniel # >> | 23 | 2010 | R | 60 | 30 | 30 | 6 | 13 | 5.20 | .324 | 1.42 | 9.2 | 3.6 | 5.2 | 185.1 | 190 | 111 | 107 | 27 | 74 | 107 | 1 | 0 | 0 | 0 | 12 | 2 | 5 | 4.97 |
| SP | Millwood, K.Millwood, Kevin # >> | 25 | 1999 | R | 52 | 29 | 29 | 10 | 9 | 4.73 | .307 | 1.31 | 8.9 | 3.0 | 5.6 | 186.1 | 184 | 102 | 98 | 33 | 61 | 115 | 0 | 0 | 0 | 0 | 12 | 3 | 3 | 5.10 |
| RP | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 94 | 79 | 0 | 9 | 2 | 2.84 | .282 | 1.16 | 6.7 | 3.8 | 9.9 | 107.2 | 80 | 34 | 34 | 9 | 45 | 118 | 0 | 14 | 2 | 0 | 0 | 2 | 0 | 3.21 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 52 | 0 | 5 | 3 | 3.97 | .295 | 1.25 | 8.4 | 2.9 | 8.8 | 59.0 | 55 | 27 | 26 | 5 | 19 | 58 | 0 | 7 | 2 | 0 | 0 | 0 | 5 | 3.10 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 60 | 42 | 0 | 1 | 3 | 2.76 | .255 | 1.01 | 8.4 | 0.8 | 8.8 | 45.2 | 42 | 14 | 14 | 6 | 4 | 44 | 0 | 5 | 1 | 0 | 0 | 1 | 1 | 3.11 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 45 | 21 | 0 | 1 | 0 | 3.38 | .301 | 1.29 | 6.8 | 4.9 | 9.8 | 24.0 | 18 | 9 | 9 | 4 | 13 | 26 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.63 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 6 | 0 | 0 | 1 | 7.71 | .364 | 1.71 | 6.8 | 11.3 | 2.3 | 4.2 | 3 | 4 | 4 | 0 | 5 | 1 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 6.25 |