| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 30 | 30 | 12 | 11 | 3.34 | .264 | 1.06 | 7.1 | 2.5 | 8.2 | 234.2 | 184 | 90 | 87 | 28 | 64 | 212 | 13 | 0 | 0 | 1 | 21 | 5 | 5 | 3.63 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 30 | 30 | 12 | 10 | 4.95 | .332 | 1.47 | 9.4 | 3.9 | 8.1 | 194.2 | 202 | 109 | 107 | 28 | 84 | 174 | 2 | 0 | 0 | 2 | 13 | 4 | 3 | 4.44 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 29 | 29 | 9 | 13 | 4.38 | .311 | 1.32 | 9.3 | 2.7 | 4.9 | 213.2 | 219 | 112 | 104 | 26 | 64 | 117 | 4 | 0 | 0 | 1 | 15 | 7 | 5 | 4.49 |
| SP | Marichal, J.Marichal, Juan # >> | 29 | 1966 | R | 77 | 30 | 30 | 8 | 16 | 6.79 | .363 | 1.70 | 11.9 | 3.3 | 5.3 | 191.0 | 253 | 152 | 144 | 40 | 71 | 113 | 6 | 0 | 0 | 0 | 9 | 3 | 1 | 5.70 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 29 | 29 | 6 | 13 | 5.77 | .340 | 1.52 | 10.7 | 3.0 | 5.9 | 149.2 | 177 | 102 | 96 | 21 | 50 | 97 | 0 | 0 | 0 | 0 | 7 | 4 | 5 | 4.62 |
| CL | Adams, M.Adams, Mike † $ >> | 31 | 2009 | R | 99 | 45 | 0 | 4 | 6 | 3.94 | .315 | 1.34 | 7.8 | 4.4 | 8.2 | 45.2 | 39 | 21 | 20 | 3 | 22 | 41 | 0 | 24 | 4 | 0 | 0 | 2 | 2 | 3.64 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 89 | 30 | 0 | 5 | 0 | 3.71 | .339 | 1.54 | 8.7 | 5.5 | 8.3 | 26.2 | 25 | 14 | 11 | 4 | 16 | 24 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 5.00 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 80 | 17 | 0 | 2 | 0 | 3.45 | .288 | 1.21 | 6.0 | 5.4 | 7.2 | 15.2 | 10 | 8 | 6 | 2 | 9 | 12 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 4.93 |