| SP | Koufax, S.Koufax, Sandy † >> | 30 | 1965 | L | 97 | 18 | 18 | 9 | 6 | 3.31 | .257 | 1.02 | 7.0 | 2.2 | 8.5 | 149.1 | 116 | 55 | 55 | 18 | 37 | 141 | 8 | 0 | 0 | 0 | 9 | 2 | 5 | 3.46 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 18 | 18 | 9 | 8 | 4.01 | .304 | 1.29 | 9.0 | 2.7 | 9.3 | 125.2 | 125 | 60 | 56 | 17 | 37 | 129 | 2 | 0 | 0 | 2 | 8 | 3 | 2 | 3.66 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 17 | 17 | 3 | 10 | 6.17 | .341 | 1.53 | 11.1 | 2.7 | 3.9 | 105.0 | 129 | 78 | 72 | 15 | 32 | 45 | 0 | 0 | 0 | 0 | 4 | 2 | 3 | 4.97 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 58 | 16 | 16 | 4 | 8 | 5.81 | .350 | 1.60 | 11.1 | 3.4 | 4.6 | 114.2 | 140 | 75 | 74 | 18 | 43 | 58 | 4 | 0 | 0 | 1 | 4 | 2 | 3 | 5.22 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 34 | 0 | 4 | 2 | 5.79 | .329 | 1.45 | 10.2 | 2.9 | 10.5 | 37.1 | 42 | 24 | 24 | 5 | 12 | 43 | 0 | 4 | 4 | 0 | 0 | 1 | 3 | 3.49 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 57 | 1 | 1 | 0 | 0 | 10.13 | .333 | 1.50 | 10.8 | 3.6 | 3.6 | 5.1 | 6 | 6 | 6 | 1 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.00 |