| SP | McNally, D.McNally, Dave † >> | 26 | 1968 | L | 96 | 24 | 24 | 13 | 10 | 2.62 | .260 | 1.04 | 7.2 | 2.2 | 4.8 | 203.0 | 162 | 66 | 59 | 12 | 50 | 108 | 14 | 0 | 0 | 2 | 17 | 2 | 4 | 3.47 |
| SP | Snell, B.Snell, Blake # >> | 25 | 2018 | L | 81 | 24 | 24 | 6 | 14 | 5.25 | .322 | 1.41 | 8.1 | 4.6 | 7.9 | 142.1 | 128 | 90 | 83 | 21 | 73 | 124 | 1 | 0 | 0 | 1 | 7 | 2 | 6 | 4.76 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 23 | 23 | 5 | 12 | 5.91 | .353 | 1.61 | 11.0 | 3.5 | 6.2 | 149.1 | 182 | 103 | 98 | 32 | 58 | 103 | 5 | 0 | 0 | 0 | 8 | 4 | 1 | 5.66 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 67 | 21 | 21 | 8 | 9 | 4.79 | .307 | 1.27 | 9.2 | 2.2 | 8.4 | 141.0 | 144 | 79 | 75 | 25 | 35 | 131 | 2 | 0 | 0 | 0 | 9 | 8 | 3 | 4.36 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 23 | 23 | 8 | 14 | 5.25 | .334 | 1.46 | 10.5 | 2.6 | 5.1 | 161.0 | 188 | 98 | 94 | 24 | 47 | 92 | 10 | 0 | 0 | 2 | 10 | 7 | 2 | 4.80 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 53 | 0 | 2 | 2 | 2.13 | .276 | 1.11 | 6.2 | 3.8 | 10.1 | 76.0 | 52 | 25 | 18 | 4 | 32 | 85 | 0 | 5 | 2 | 0 | 0 | 3 | 1 | 2.83 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 40 | 0 | 2 | 3 | 5.45 | .316 | 1.39 | 9.2 | 3.5 | 8.1 | 39.2 | 40 | 24 | 24 | 9 | 15 | 35 | 0 | 1 | 1 | 0 | 0 | 0 | 3 | 5.36 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 58 | 28 | 0 | 0 | 2 | 3.10 | .287 | 1.17 | 6.5 | 4.0 | 10.2 | 29.0 | 21 | 11 | 10 | 2 | 13 | 33 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 3.07 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 57 | 2 | 2 | 1 | 0 | 3.32 | .269 | 1.00 | 8.5 | 0.5 | 4.3 | 19.0 | 18 | 7 | 7 | 4 | 1 | 9 | 1 | 0 | 0 | 0 | 1 | 2 | 0 | 5.26 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 15 | 0 | 0 | 2 | 5.03 | .322 | 1.37 | 10.4 | 2.4 | 9.9 | 19.2 | 22 | 11 | 11 | 4 | 5 | 21 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.47 |