| SP | Arrieta, J.Arrieta, Jake $ >> | 29 | 2015 | R | 93 | 24 | 24 | 9 | 8 | 3.80 | .281 | 1.16 | 8.3 | 2.2 | 8.3 | 168.1 | 155 | 71 | 71 | 22 | 41 | 154 | 4 | 0 | 0 | 1 | 12 | 1 | 5 | 3.62 |
| SP | Richard, J.Richard, J.R. $ >> | 30 | 1980 | R | 90 | 23 | 23 | 12 | 6 | 3.40 | .284 | 1.16 | 7.5 | 3.0 | 6.2 | 153.2 | 128 | 59 | 58 | 14 | 51 | 105 | 0 | 0 | 0 | 0 | 16 | 4 | 2 | 3.90 |
| SP | Brown, M.Brown, Mordecai † >> | 32 | 1908 | R | 85 | 23 | 23 | 18 | 4 | 2.38 | .249 | 0.97 | 6.9 | 1.8 | 4.0 | 185.1 | 142 | 53 | 49 | 14 | 38 | 82 | 8 | 0 | 0 | 2 | 19 | 4 | 4 | 3.78 |
| SP | Fernandez, S.Fernandez, Sid † >> | 23 | 1985 | L | 49 | 23 | 23 | 12 | 8 | 3.32 | .284 | 1.17 | 7.0 | 3.6 | 7.8 | 154.1 | 120 | 61 | 57 | 15 | 61 | 133 | 1 | 0 | 0 | 0 | 15 | 3 | 3 | 3.79 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 53 | 0 | 1 | 2 | 2.67 | .263 | 1.07 | 6.3 | 3.5 | 8.6 | 60.2 | 42 | 18 | 18 | 9 | 23 | 57 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.20 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 24 | 0 | 2 | 1 | 2.15 | .221 | 0.85 | 6.5 | 1.2 | 5.9 | 29.1 | 21 | 8 | 7 | 4 | 4 | 19 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 3.90 |
| RP | Fingers, R.Fingers, Rollie >> | 35 | 1981 | R | 53 | 16 | 0 | 1 | 2 | 2.77 | .264 | 1.08 | 7.6 | 2.1 | 5.5 | 13.0 | 11 | 4 | 4 | 2 | 3 | 8 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.46 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 55 | 12 | 0 | 1 | 0 | 1.80 | .286 | 1.20 | 5.4 | 5.4 | 4.5 | 10.0 | 6 | 2 | 2 | 1 | 6 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.10 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 13 | 0 | 2 | 1 | 3.12 | .300 | 1.25 | 7.7 | 3.6 | 8.1 | 57.2 | 49 | 20 | 20 | 4 | 23 | 51 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.44 |
| CL | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 93 | 38 | 0 | 0 | 4 | 3.71 | .297 | 1.24 | 6.4 | 4.8 | 10.3 | 34.0 | 24 | 15 | 14 | 2 | 18 | 39 | 0 | 32 | 4 | 0 | 0 | 1 | 1 | 3.15 |