| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 31 | 31 | 12 | 14 | 3.68 | .295 | 1.24 | 8.8 | 2.4 | 9.6 | 207.2 | 202 | 96 | 85 | 26 | 56 | 220 | 1 | 0 | 0 | 0 | 18 | 3 | 3 | 3.36 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 30 | 30 | 16 | 10 | 4.12 | .304 | 1.29 | 8.4 | 3.2 | 6.2 | 235.2 | 220 | 112 | 108 | 32 | 83 | 161 | 12 | 0 | 0 | 1 | 15 | 6 | 6 | 4.54 |
| SP | Bender, C.Bender, Chief # >> | 26 | 1910 | R | 72 | 30 | 30 | 6 | 18 | 5.36 | .327 | 1.45 | 10.2 | 2.8 | 5.2 | 213.1 | 242 | 135 | 127 | 24 | 67 | 123 | 6 | 0 | 0 | 1 | 13 | 2 | 12 | 4.28 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 30 | 30 | 9 | 13 | 5.56 | .344 | 1.56 | 10.0 | 4.1 | 4.9 | 178.0 | 197 | 119 | 110 | 26 | 81 | 97 | 0 | 0 | 0 | 0 | 12 | 2 | 3 | 5.21 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 57 | 29 | 29 | 7 | 17 | 6.38 | .359 | 1.67 | 11.3 | 3.7 | 5.6 | 204.2 | 257 | 148 | 145 | 29 | 84 | 127 | 8 | 0 | 0 | 0 | 7 | 3 | 1 | 4.88 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 79 | 0 | 7 | 3 | 3.69 | .291 | 1.23 | 6.4 | 4.6 | 9.1 | 105.0 | 75 | 47 | 43 | 6 | 54 | 106 | 0 | 12 | 5 | 0 | 0 | 0 | 3 | 3.27 |
| RP | Williams, D.Williams, Devin # >> | 28 | 2023 | R | 73 | 59 | 0 | 5 | 3 | 4.08 | .319 | 1.39 | 7.6 | 4.9 | 9.7 | 64.0 | 54 | 35 | 29 | 11 | 35 | 69 | 0 | 4 | 0 | 0 | 0 | 1 | 2 | 4.77 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 39 | 0 | 3 | 1 | 4.87 | .335 | 1.49 | 11.3 | 2.3 | 7.6 | 44.1 | 55 | 26 | 24 | 7 | 11 | 37 | 0 | 5 | 3 | 0 | 0 | 1 | 2 | 4.20 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 57 | 36 | 0 | 1 | 1 | 4.86 | .339 | 1.54 | 9.7 | 4.1 | 9.0 | 37.0 | 40 | 23 | 20 | 4 | 17 | 37 | 0 | 2 | 0 | 0 | 0 | 0 | 5 | 3.78 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 51 | 31 | 0 | 1 | 2 | 4.04 | .296 | 1.26 | 9.8 | 1.8 | 8.0 | 35.2 | 38 | 17 | 16 | 3 | 7 | 31 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 2.94 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 14 | 0 | 1 | 0 | 4.50 | .354 | 1.64 | 8.7 | 6.1 | 5.8 | 28.0 | 27 | 14 | 14 | 2 | 19 | 18 | 0 | 1 | 0 | 0 | 0 | 0 | 4 | 4.68 |