| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 12 | 12 | 7 | 2 | 3.33 | .292 | 1.22 | 8.7 | 2.3 | 4.1 | 81.0 | 78 | 32 | 30 | 6 | 21 | 37 | 1 | 0 | 0 | 1 | 8 | 1 | 2 | 3.86 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 13 | 13 | 7 | 3 | 4.25 | .292 | 1.23 | 8.2 | 2.9 | 6.6 | 78.1 | 71 | 38 | 37 | 14 | 25 | 57 | 1 | 0 | 0 | 0 | 8 | 1 | 2 | 4.87 |
| SP | Reulbach, E.Reulbach, Ed $$ >> | 24 | 1906 | R | 60 | 12 | 12 | 5 | 3 | 3.20 | .286 | 1.19 | 6.7 | 4.1 | 3.9 | 81.2 | 60 | 31 | 29 | 7 | 37 | 35 | 1 | 0 | 0 | 0 | 8 | 1 | 3 | 4.67 |
| CL | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 28 | 0 | 2 | 4 | 1.95 | .259 | 1.01 | 6.7 | 2.7 | 7.7 | 27.2 | 20 | 7 | 6 | 0 | 8 | 23 | 0 | 19 | 1 | 0 | 0 | 1 | 0 | 2.30 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 85 | 28 | 0 | 1 | 1 | 3.94 | .336 | 1.52 | 9.6 | 4.3 | 10.2 | 29.2 | 31 | 13 | 13 | 4 | 14 | 33 | 0 | 0 | 2 | 0 | 0 | 0 | 6 | 3.97 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 20 | 0 | 1 | 1 | 5.16 | .269 | 1.10 | 6.5 | 3.7 | 13.5 | 22.2 | 16 | 13 | 13 | 3 | 9 | 33 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 3.00 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 16 | 0 | 1 | 1 | 4.30 | .266 | 1.04 | 6.3 | 3.1 | 9.0 | 23.0 | 16 | 11 | 11 | 3 | 8 | 23 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.87 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 74 | 8 | 0 | 0 | 0 | 6.00 | .372 | 1.78 | 5.0 | 11.0 | 6.0 | 9.0 | 5 | 7 | 6 | 1 | 11 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.78 |
| RP | Rodriguez, F.Rodriguez, Felix >> | 29 | 2001 | R | 42 | 8 | 0 | 0 | 1 | 8.44 | .333 | 1.50 | 12.6 | 1.8 | 9.0 | 5.1 | 7 | 6 | 5 | 1 | 1 | 5 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.20 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 59 | 11 | 0 | 0 | 1 | 6.23 | .278 | 1.15 | 10.1 | 1.1 | 11.3 | 8.2 | 9 | 6 | 6 | 2 | 1 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.13 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 55 | 10 | 0 | 0 | 0 | 7.27 | .395 | 1.96 | 14.6 | 4.5 | 13.5 | 8.2 | 13 | 9 | 7 | 2 | 4 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.75 |