| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 18 | 18 | 4 | 8 | 4.77 | .329 | 1.46 | 10.6 | 2.6 | 5.5 | 109.1 | 128 | 65 | 58 | 14 | 32 | 67 | 1 | 0 | 0 | 0 | 8 | 1 | 2 | 4.35 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 17 | 17 | 5 | 7 | 4.19 | .314 | 1.36 | 8.8 | 3.4 | 5.0 | 118.0 | 116 | 57 | 55 | 10 | 44 | 66 | 2 | 0 | 0 | 1 | 9 | 2 | 1 | 4.15 |
| CL | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 93 | 41 | 0 | 3 | 4 | 2.31 | .259 | 1.05 | 5.8 | 3.8 | 10.4 | 50.2 | 32 | 14 | 13 | 1 | 21 | 58 | 0 | 19 | 2 | 0 | 0 | 0 | 0 | 2.20 |
| SU | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 48 | 0 | 4 | 2 | 2.44 | .275 | 1.10 | 8.5 | 1.5 | 10.1 | 55.1 | 52 | 16 | 15 | 5 | 9 | 62 | 0 | 1 | 4 | 0 | 0 | 2 | 0 | 2.53 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 48 | 0 | 4 | 0 | 3.61 | .297 | 1.20 | 6.8 | 4.1 | 8.9 | 62.1 | 47 | 28 | 25 | 4 | 28 | 61 | 0 | 0 | 1 | 0 | 0 | 4 | 1 | 3.42 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 48 | 0 | 3 | 1 | 3.08 | .339 | 1.52 | 7.1 | 6.8 | 11.6 | 52.2 | 41 | 22 | 18 | 5 | 39 | 67 | 0 | 1 | 2 | 0 | 0 | 1 | 3 | 3.98 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 39 | 0 | 1 | 2 | 4.91 | .362 | 1.68 | 9.8 | 5.3 | 8.0 | 44.0 | 48 | 24 | 24 | 4 | 26 | 39 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.25 |