| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 24 | 24 | 9 | 4 | 3.35 | .291 | 1.23 | 8.2 | 2.9 | 9.2 | 163.2 | 148 | 66 | 61 | 16 | 53 | 167 | 0 | 0 | 0 | 0 | 14 | 1 | 4 | 3.22 |
| SP | Pfiester, J.Pfiester, Jack # >> | 28 | 1906 | L | 73 | 23 | 23 | 5 | 10 | 5.29 | .336 | 1.50 | 10.1 | 3.5 | 5.9 | 156.2 | 175 | 97 | 92 | 17 | 60 | 103 | 4 | 0 | 0 | 0 | 10 | 3 | 2 | 4.31 |
| SP | Caldwell, R.Caldwell, Ray # >> | 26 | 1914 | R | 63 | 23 | 23 | 11 | 5 | 3.35 | .300 | 1.26 | 8.6 | 2.7 | 5.2 | 153.0 | 147 | 64 | 57 | 12 | 46 | 89 | 1 | 0 | 0 | 0 | 14 | 4 | 0 | 3.84 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 60 | 0 | 4 | 7 | 4.05 | .310 | 1.32 | 7.5 | 4.4 | 8.4 | 93.1 | 78 | 42 | 42 | 10 | 45 | 87 | 0 | 11 | 7 | 0 | 0 | 3 | 0 | 4.08 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 45 | 0 | 5 | 8 | 4.47 | .337 | 1.51 | 7.2 | 6.5 | 10.3 | 54.1 | 43 | 27 | 27 | 6 | 39 | 62 | 0 | 2 | 5 | 0 | 0 | 1 | 1 | 4.37 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 26 | 0 | 4 | 5 | 4.95 | .335 | 1.51 | 8.6 | 5.2 | 4.0 | 43.2 | 41 | 24 | 24 | 5 | 25 | 19 | 0 | 0 | 2 | 0 | 0 | 0 | 4 | 5.37 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 12 | 0 | 0 | 2 | 5.40 | .366 | 1.73 | 10.8 | 4.8 | 6.6 | 15.0 | 18 | 12 | 9 | 1 | 8 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 4.00 |