| SP | deGrom, J.deGrom, Jacob # >> | 33 | 2021 | R | 100 | 23 | 23 | 7 | 4 | 3.35 | .258 | 1.02 | 7.9 | 1.3 | 9.6 | 161.0 | 142 | 61 | 60 | 24 | 23 | 171 | 0 | 0 | 0 | 0 | 16 | 3 | 0 | 3.30 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 23 | 23 | 11 | 7 | 3.21 | .290 | 1.20 | 8.7 | 2.1 | 4.9 | 179.2 | 174 | 67 | 64 | 13 | 41 | 97 | 9 | 0 | 0 | 3 | 16 | 5 | 2 | 3.63 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 22 | 22 | 8 | 8 | 6.67 | .366 | 1.71 | 11.6 | 3.9 | 5.0 | 133.2 | 172 | 111 | 99 | 24 | 57 | 74 | 0 | 0 | 0 | 0 | 8 | 2 | 1 | 5.56 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 61 | 0 | 8 | 8 | 4.39 | .278 | 1.14 | 8.0 | 2.3 | 8.6 | 84.0 | 75 | 47 | 41 | 9 | 21 | 80 | 0 | 5 | 8 | 0 | 0 | 1 | 2 | 3.27 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 89 | 53 | 0 | 1 | 7 | 4.48 | .307 | 1.31 | 8.5 | 3.4 | 8.9 | 66.1 | 62 | 33 | 33 | 5 | 25 | 65 | 0 | 7 | 4 | 0 | 0 | 1 | 2 | 3.20 |
| RP | Hochevar, L.Hochevar, Luke † >> | 30 | 2013 | R | 77 | 43 | 0 | 3 | 1 | 2.65 | .243 | 0.92 | 6.2 | 2.1 | 10.8 | 51.0 | 35 | 16 | 15 | 4 | 12 | 61 | 0 | 6 | 0 | 0 | 0 | 2 | 0 | 2.45 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 28 | 0 | 2 | 2 | 3.55 | .288 | 1.18 | 8.5 | 2.2 | 7.9 | 33.0 | 31 | 13 | 13 | 3 | 8 | 29 | 0 | 1 | 3 | 0 | 0 | 1 | 3 | 3.24 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 14 | 0 | 5 | 0 | 3.38 | .339 | 1.50 | 7.5 | 6.0 | 5.3 | 24.0 | 20 | 10 | 9 | 1 | 16 | 14 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 4.50 |