| SP | deGrom, J.deGrom, Jacob >> | 37 | 2025 | R | 97 | 21 | 21 | 6 | 8 | 4.23 | .304 | 1.27 | 8.5 | 2.9 | 8.6 | 117.0 | 111 | 55 | 55 | 16 | 38 | 112 | 0 | 0 | 0 | 0 | 15 | 4 | 2 | 3.94 |
| SP | Skenes, P.Skenes, Paul >> | 23 | 2025 | R | 95 | 20 | 20 | 9 | 6 | 3.41 | .285 | 1.18 | 7.9 | 2.7 | 8.8 | 118.2 | 104 | 46 | 45 | 7 | 36 | 116 | 0 | 0 | 0 | 0 | 13 | 2 | 3 | 2.77 |
| SP | Gausman, K.Gausman, Kevin >> | 34 | 2025 | R | 84 | 20 | 20 | 8 | 6 | 3.59 | .328 | 1.43 | 10.1 | 2.8 | 7.8 | 123.0 | 138 | 52 | 49 | 13 | 38 | 106 | 0 | 0 | 0 | 0 | 12 | 4 | 1 | 3.67 |
| SP | Burrows, M.Burrows, Mike # >> | 25 | 2025 | R | 62 | 19 | 19 | 4 | 7 | 4.94 | .309 | 1.33 | 8.7 | 3.3 | 9.4 | 82.0 | 79 | 45 | 45 | 8 | 30 | 86 | 0 | 0 | 0 | 0 | 1 | 1 | 5 | 3.30 |
| CL | Clarke, T.Clarke, Taylor † >> | 32 | 2025 | R | 87 | 46 | 0 | 3 | 4 | 2.70 | .265 | 1.06 | 6.8 | 2.7 | 9.2 | 50.0 | 38 | 15 | 15 | 5 | 15 | 51 | 0 | 23 | 0 | 0 | 0 | 1 | 2 | 3.22 |
| RP | Miller, S.Miller, Shelby >> | 34 | 2025 | R | 82 | 55 | 0 | 6 | 3 | 3.96 | .308 | 1.25 | 6.8 | 4.4 | 9.5 | 75.0 | 57 | 34 | 33 | 4 | 37 | 79 | 0 | 0 | 1 | 0 | 0 | 6 | 1 | 3.31 |
| RP | Rogers, T.Rogers, Tyler >> | 34 | 2025 | R | 67 | 48 | 0 | 1 | 0 | 3.92 | .312 | 1.29 | 9.8 | 2.0 | 5.9 | 59.2 | 64 | 27 | 26 | 1 | 13 | 39 | 0 | 3 | 2 | 0 | 0 | 4 | 0 | 2.76 |
| RP | Rodriguez, M.Rodriguez, Manuel >> | 28 | 2025 | R | 58 | 28 | 0 | 3 | 2 | 7.11 | .349 | 1.61 | 11.6 | 3.2 | 8.1 | 31.2 | 40 | 25 | 25 | 8 | 11 | 28 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.61 |