| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 15 | 15 | 5 | 6 | 4.50 | .285 | 1.15 | 8.2 | 2.2 | 11.0 | 92.0 | 84 | 46 | 46 | 12 | 22 | 112 | 0 | 0 | 0 | 0 | 7 | 4 | 0 | 3.11 |
| SP | Schwellenbach, S.Schwellenbach, Spencer >> | 25 | 2025 | R | 87 | 15 | 15 | 8 | 4 | 3.65 | .300 | 1.29 | 8.8 | 2.8 | 7.0 | 101.0 | 99 | 45 | 41 | 11 | 31 | 79 | 1 | 0 | 0 | 0 | 9 | 0 | 0 | 3.77 |
| SP | Imanaga, S.Imanaga, Shota # >> | 31 | 2025 | L | 83 | 15 | 15 | 3 | 8 | 7.09 | .357 | 1.65 | 11.6 | 3.3 | 7.9 | 66.0 | 85 | 56 | 52 | 17 | 24 | 58 | 0 | 0 | 0 | 0 | 4 | 1 | 3 | 5.73 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 100 | 39 | 0 | 2 | 0 | 2.56 | .251 | 0.97 | 5.4 | 3.5 | 11.3 | 52.2 | 31 | 15 | 15 | 5 | 20 | 65 | 0 | 3 | 0 | 0 | 0 | 2 | 2 | 3.02 |
| RP | Munoz, A.Munoz, Andres >> | 26 | 2025 | R | 90 | 33 | 0 | 3 | 1 | 2.83 | .315 | 1.35 | 7.5 | 4.8 | 11.2 | 41.1 | 34 | 13 | 13 | 6 | 22 | 51 | 0 | 4 | 2 | 0 | 0 | 1 | 0 | 4.10 |
| RP | Fisher, B.Fisher, Braydon >> | 24 | 2025 | R | 89 | 28 | 0 | 1 | 1 | 2.64 | .252 | 1.01 | 6.0 | 3.3 | 11.4 | 30.2 | 20 | 10 | 9 | 1 | 11 | 38 | 0 | 5 | 2 | 0 | 0 | 0 | 0 | 2.00 |
| RP | Sterner, J.Sterner, Justin >> | 28 | 2025 | R | 78 | 17 | 0 | 0 | 1 | 5.89 | .313 | 1.36 | 10.0 | 2.5 | 10.0 | 18.1 | 20 | 12 | 12 | 6 | 5 | 20 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 5.94 |
| RP | Estrada, J.Estrada, Jeremiah >> | 26 | 2025 | R | 65 | 22 | 0 | 0 | 2 | 10.35 | .439 | 2.30 | 14.4 | 6.3 | 12.2 | 20.0 | 32 | 23 | 23 | 5 | 14 | 27 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 5.80 |
| SP | Kirby, G.Kirby, George >> | 27 | 2025 | R | 66 | 3 | 0 | 1 | 0 | 2.35 | .303 | 1.30 | 6.4 | 6.4 | 12.9 | 7.2 | 5 | 2 | 2 | 0 | 5 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.29 |
| SP | Kelly, M.Kelly, Merrill >> | 36 | 2025 | R | 74 | 13 | 0 | 3 | 2 | 4.47 | .302 | 1.28 | 8.7 | 2.9 | 6.1 | 52.1 | 50 | 28 | 26 | 8 | 17 | 35 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.69 |