| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 19 | 19 | 10 | 5 | 3.79 | .314 | 1.34 | 9.7 | 2.4 | 10.3 | 118.2 | 127 | 50 | 50 | 16 | 32 | 135 | 0 | 0 | 0 | 0 | 15 | 4 | 2 | 3.39 |
| SP | Schwellenbach, S.Schwellenbach, Spencer † # >> | 25 | 2025 | R | 87 | 18 | 18 | 9 | 3 | 3.46 | .264 | 1.05 | 8.0 | 1.5 | 10.0 | 127.1 | 113 | 49 | 49 | 21 | 21 | 141 | 0 | 0 | 0 | 0 | 12 | 3 | 2 | 3.50 |
| SP | Cabrera, E.Cabrera, Edward >> | 27 | 2025 | R | 70 | 17 | 17 | 5 | 5 | 5.38 | .365 | 1.68 | 10.8 | 4.4 | 9.1 | 88.2 | 106 | 53 | 53 | 12 | 43 | 89 | 0 | 0 | 0 | 0 | 5 | 4 | 5 | 4.35 |
| SP | Woods Richardson, S.Woods Richardson, Simeon >> | 24 | 2025 | R | 59 | 17 | 17 | 4 | 4 | 4.30 | .318 | 1.38 | 8.2 | 4.2 | 6.8 | 90.0 | 82 | 48 | 43 | 13 | 42 | 68 | 0 | 0 | 0 | 0 | 4 | 2 | 4 | 4.83 |
| SP | Flaherty, J.Flaherty, Jack >> | 29 | 2025 | R | 57 | 17 | 17 | 3 | 6 | 5.87 | .319 | 1.39 | 9.1 | 3.4 | 9.8 | 87.1 | 88 | 57 | 57 | 23 | 33 | 95 | 0 | 0 | 0 | 0 | 6 | 2 | 2 | 5.46 |
| RP | Clarke, T.Clarke, Taylor >> | 32 | 2025 | R | 87 | 46 | 0 | 2 | 4 | 3.11 | .279 | 1.13 | 7.4 | 2.9 | 9.7 | 63.2 | 52 | 23 | 22 | 7 | 20 | 68 | 0 | 7 | 5 | 0 | 0 | 2 | 3 | 3.33 |
| RP | Mattson, I.Mattson, Isaac >> | 29 | 2025 | R | 64 | 35 | 0 | 3 | 3 | 2.49 | .253 | 0.99 | 5.9 | 3.1 | 6.9 | 43.1 | 28 | 12 | 12 | 4 | 15 | 33 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 3.79 |
| RP | Koenig, J.Koenig, Jared >> | 31 | 2025 | L | 57 | 28 | 0 | 1 | 0 | 4.78 | .333 | 1.44 | 9.0 | 3.9 | 8.7 | 32.0 | 32 | 18 | 17 | 6 | 14 | 31 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 5.00 |
| SP | Wacha, M.Wacha, Michael >> | 33 | 2025 | R | 49 | 2 | 0 | 1 | 0 | 0.00 | .500 | 3.00 | 13.5 | 13.5 | 13.5 | 2.0 | 3 | 0 | 0 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.50 |
| SP | Priester, Q.Priester, Quinn >> | 24 | 2025 | R | 53 | 15 | 0 | 3 | 5 | 5.10 | .375 | 1.77 | 9.3 | 6.6 | 7.8 | 30.0 | 31 | 17 | 17 | 4 | 22 | 26 | 0 | 1 | 1 | 0 | 0 | 1 | 3 | 5.30 |