| SP | Hershiser, O.Hershiser, Orel † >> | 27 | 1985 | R | 97 | 26 | 26 | 13 | 8 | 3.11 | .278 | 1.14 | 7.3 | 3.0 | 5.5 | 193.2 | 157 | 69 | 67 | 12 | 64 | 118 | 4 | 0 | 0 | 1 | 19 | 3 | 2 | 3.63 |
| SP | Mussina, M.Mussina, Mike >> | 34 | 2002 | R | 72 | 25 | 25 | 10 | 10 | 3.40 | .303 | 1.29 | 8.7 | 3.0 | 5.4 | 169.1 | 163 | 70 | 64 | 14 | 56 | 102 | 0 | 0 | 0 | 0 | 18 | 2 | 4 | 3.90 |
| SP | Grant, M.Grant, Mudcat >> | 26 | 1961 | R | 66 | 25 | 25 | 5 | 10 | 5.99 | .376 | 1.77 | 10.4 | 5.6 | 5.7 | 145.2 | 167 | 110 | 97 | 20 | 91 | 92 | 0 | 0 | 0 | 0 | 9 | 5 | 9 | 5.51 |
| SP | Carlton, S.Carlton, Steve >> | 39 | 1983 | L | 60 | 24 | 24 | 7 | 10 | 5.08 | .328 | 1.42 | 9.4 | 3.4 | 6.5 | 163.0 | 171 | 99 | 92 | 15 | 61 | 118 | 5 | 0 | 0 | 1 | 11 | 7 | 9 | 4.00 |
| RP | Alvarado, J.Alvarado, Jose >> | 27 | 2022 | L | 80 | 59 | 0 | 2 | 5 | 4.68 | .331 | 1.47 | 7.5 | 5.8 | 10.9 | 65.1 | 54 | 36 | 34 | 6 | 42 | 79 | 0 | 6 | 4 | 0 | 0 | 1 | 3 | 3.75 |
| RP | Andersen, L.Andersen, Larry >> | 28 | 1981 | R | 74 | 51 | 0 | 5 | 3 | 3.79 | .284 | 1.19 | 8.7 | 2.0 | 5.5 | 71.1 | 69 | 31 | 30 | 7 | 16 | 43 | 0 | 6 | 7 | 0 | 0 | 0 | 0 | 3.75 |
| RP | Leclerc, J.Leclerc, Jose >> | 23 | 2017 | R | 66 | 29 | 0 | 3 | 4 | 5.54 | .435 | 2.31 | 10.4 | 10.4 | 7.6 | 26.0 | 30 | 16 | 16 | 5 | 30 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 7.27 |
| RP | Timlin, M.Timlin, Mike >> | 29 | 1995 | R | 61 | 11 | 0 | 0 | 0 | 0.00 | .289 | 1.22 | 7.2 | 4.5 | 8.1 | 10.2 | 8 | 0 | 0 | 0 | 5 | 9 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 2.70 |
| RP | Navarro, J.Navarro, Julio >> | 28 | 1964 | R | 56 | 12 | 0 | 0 | 0 | 6.91 | .394 | 1.95 | 9.6 | 8.4 | 3.2 | 14.1 | 15 | 11 | 11 | 2 | 13 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.93 |