| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 30 | 30 | 12 | 14 | 3.75 | .270 | 1.07 | 7.6 | 2.1 | 9.9 | 216.0 | 182 | 92 | 90 | 31 | 50 | 237 | 7 | 0 | 0 | 0 | 20 | 8 | 4 | 3.48 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 30 | 30 | 8 | 12 | 5.03 | .325 | 1.43 | 9.4 | 3.5 | 8.9 | 173.2 | 181 | 101 | 97 | 35 | 67 | 172 | 0 | 0 | 0 | 0 | 12 | 3 | 7 | 4.86 |
| SP | Flaherty, J.Flaherty, Jack >> | 23 | 2019 | R | 82 | 29 | 29 | 7 | 12 | 5.82 | .347 | 1.57 | 9.3 | 4.9 | 9.5 | 151.2 | 156 | 99 | 98 | 32 | 82 | 160 | 0 | 0 | 0 | 0 | 10 | 4 | 5 | 5.34 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 78 | 29 | 29 | 13 | 10 | 5.12 | .315 | 1.36 | 9.2 | 3.0 | 9.2 | 193.1 | 198 | 112 | 110 | 37 | 65 | 198 | 4 | 0 | 0 | 0 | 11 | 4 | 2 | 4.51 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 66 | 28 | 28 | 8 | 12 | 4.83 | .330 | 1.45 | 10.7 | 2.4 | 6.1 | 188.1 | 223 | 111 | 101 | 30 | 50 | 128 | 3 | 0 | 0 | 1 | 12 | 5 | 7 | 4.59 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 82 | 72 | 0 | 6 | 3 | 3.57 | .281 | 1.15 | 7.7 | 2.7 | 9.6 | 103.1 | 88 | 42 | 41 | 13 | 31 | 110 | 0 | 1 | 2 | 0 | 0 | 2 | 0 | 3.47 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 82 | 63 | 0 | 5 | 4 | 3.20 | .251 | 0.97 | 5.8 | 3.1 | 11.0 | 64.2 | 41 | 25 | 23 | 9 | 22 | 78 | 0 | 2 | 1 | 0 | 0 | 2 | 3 | 3.52 |
| RP | Rodney, F.Rodney, Fernando >> | 35 | 2012 | R | 79 | 37 | 0 | 2 | 1 | 2.00 | .246 | 0.98 | 6.6 | 2.2 | 9.6 | 45.0 | 33 | 10 | 10 | 1 | 11 | 48 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1.89 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 78 | 32 | 0 | 2 | 2 | 3.57 | .293 | 1.22 | 7.5 | 3.6 | 8.0 | 35.1 | 29 | 16 | 14 | 3 | 14 | 31 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.63 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 46 | 0 | 2 | 8 | 4.72 | .359 | 1.62 | 9.0 | 5.7 | 12.1 | 47.2 | 47 | 27 | 25 | 8 | 30 | 63 | 0 | 20 | 8 | 0 | 0 | 3 | 1 | 4.64 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 66 | 34 | 0 | 1 | 0 | 3.76 | .272 | 1.12 | 6.9 | 3.3 | 6.9 | 38.1 | 29 | 18 | 16 | 10 | 14 | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 6.00 |
| SU | Edwards, C.Edwards, Carl >> | 24 | 2016 | R | 92 | 47 | 0 | 1 | 1 | 4.02 | .291 | 1.23 | 7.6 | 3.6 | 8.0 | 53.2 | 45 | 24 | 24 | 11 | 21 | 47 | 0 | 9 | 7 | 0 | 0 | 0 | 3 | 5.11 |