| SP | Nelson, R.Nelson, Roger # >> | 28 | 1972 | R | 88 | 24 | 24 | 6 | 5 | 4.18 | .307 | 1.32 | 8.4 | 3.5 | 6.2 | 127.0 | 119 | 65 | 59 | 15 | 49 | 88 | 0 | 0 | 0 | 0 | 7 | 1 | 1 | 4.33 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 90 | 25 | 25 | 6 | 11 | 4.21 | .313 | 1.35 | 9.4 | 2.8 | 8.9 | 173.0 | 180 | 86 | 81 | 23 | 53 | 172 | 2 | 0 | 0 | 0 | 13 | 3 | 3 | 3.71 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 94 | 23 | 23 | 7 | 8 | 3.78 | .317 | 1.38 | 8.0 | 4.5 | 9.2 | 147.2 | 131 | 65 | 62 | 14 | 73 | 150 | 1 | 0 | 0 | 1 | 13 | 2 | 3 | 3.73 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 77 | 23 | 23 | 6 | 11 | 5.90 | .341 | 1.51 | 9.8 | 3.9 | 6.1 | 135.2 | 147 | 89 | 89 | 28 | 58 | 91 | 3 | 0 | 0 | 1 | 9 | 6 | 5 | 5.77 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 74 | 23 | 23 | 5 | 8 | 4.29 | .287 | 1.19 | 7.2 | 3.4 | 9.1 | 107.0 | 86 | 54 | 51 | 15 | 41 | 108 | 0 | 0 | 0 | 0 | 3 | 2 | 3 | 4.01 |
| CL | Green, C.Green, Chad † >> | 26 | 2017 | R | 94 | 51 | 0 | 5 | 8 | 3.56 | .251 | 0.99 | 6.9 | 2.1 | 11.3 | 55.2 | 42 | 23 | 22 | 10 | 13 | 69 | 0 | 31 | 4 | 0 | 0 | 1 | 1 | 3.62 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 89 | 60 | 0 | 7 | 1 | 3.84 | .288 | 1.20 | 8.4 | 2.4 | 10.2 | 61.0 | 57 | 29 | 26 | 12 | 16 | 69 | 0 | 2 | 3 | 0 | 0 | 1 | 0 | 4.13 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 44 | 0 | 2 | 3 | 2.01 | .292 | 1.21 | 7.9 | 3.2 | 8.1 | 40.1 | 35 | 10 | 9 | 4 | 14 | 36 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 3.63 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 75 | 22 | 0 | 1 | 0 | 3.47 | .307 | 1.29 | 7.4 | 4.3 | 8.6 | 23.1 | 19 | 9 | 9 | 4 | 11 | 22 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 4.91 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 72 | 20 | 0 | 1 | 1 | 3.79 | .321 | 1.37 | 8.5 | 3.8 | 5.2 | 19.0 | 18 | 8 | 8 | 0 | 8 | 11 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 3.26 |
| SU | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 65 | 38 | 0 | 2 | 2 | 5.67 | .310 | 1.32 | 8.7 | 3.3 | 8.2 | 33.1 | 32 | 23 | 21 | 11 | 12 | 30 | 0 | 0 | 8 | 0 | 0 | 1 | 1 | 6.70 |