| SP | deGrom, J.deGrom, Jacob $ >> | 33 | 2021 | R | 100 | 13 | 13 | 4 | 5 | 4.61 | .295 | 1.22 | 9.4 | 1.5 | 10.9 | 82.0 | 86 | 43 | 42 | 17 | 14 | 99 | 0 | 0 | 0 | 0 | 8 | 3 | 0 | 3.90 |
| SP | Harden, R.Harden, Rich # >> | 27 | 2008 | R | 68 | 12 | 12 | 6 | 6 | 5.54 | .352 | 1.58 | 9.4 | 4.8 | 8.3 | 65.0 | 68 | 42 | 40 | 8 | 35 | 60 | 0 | 0 | 0 | 0 | 6 | 3 | 2 | 4.51 |
| RP | Jackson, M.Jackson, Mike >> | 30 | 1994 | R | 82 | 36 | 0 | 5 | 0 | 4.18 | .307 | 1.27 | 7.9 | 3.6 | 10.0 | 47.1 | 41 | 22 | 22 | 6 | 19 | 52 | 0 | 0 | 1 | 0 | 0 | 3 | 0 | 3.85 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 29 | 0 | 1 | 2 | 6.18 | .366 | 1.73 | 10.0 | 6.0 | 11.0 | 27.2 | 30 | 21 | 19 | 7 | 18 | 33 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 5.93 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 72 | 24 | 0 | 0 | 1 | 4.38 | .282 | 1.14 | 7.9 | 2.6 | 10.9 | 24.2 | 21 | 12 | 12 | 4 | 7 | 29 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.75 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 69 | 13 | 0 | 0 | 0 | 1.59 | .250 | 1.00 | 5.8 | 3.2 | 11.1 | 17.0 | 11 | 3 | 3 | 1 | 6 | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.35 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 64 | 11 | 0 | 1 | 0 | 4.97 | .367 | 1.66 | 8.3 | 7.5 | 9.0 | 12.2 | 11 | 7 | 7 | 2 | 10 | 12 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 5.92 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 70 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 24 | 0 | 1 | 1 | 3.20 | .315 | 1.38 | 9.4 | 3.2 | 13.0 | 25.1 | 26 | 10 | 9 | 3 | 9 | 36 | 0 | 13 | 1 | 0 | 0 | 0 | 1 | 2.76 |
| SU | Betances, D.Betances, Dellin >> | 26 | 2014 | R | 92 | 26 | 0 | 1 | 0 | 4.68 | .306 | 1.32 | 7.2 | 4.7 | 13.0 | 25.0 | 20 | 13 | 13 | 3 | 13 | 36 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.24 |