| SP | Liriano, F.Liriano, Francisco # >> | 23 | 2006 | L | 98 | 36 | 36 | 6 | 10 | 4.08 | .289 | 1.16 | 7.9 | 2.6 | 9.1 | 169.2 | 149 | 77 | 77 | 30 | 48 | 171 | 0 | 0 | 0 | 0 | 3 | 10 | 7 | 4.31 |
| SP | Perez, O.Perez, Odalis # >> | 25 | 2002 | L | 81 | 35 | 35 | 14 | 13 | 4.18 | .293 | 1.20 | 8.5 | 2.3 | 6.1 | 228.0 | 215 | 108 | 106 | 22 | 59 | 155 | 1 | 0 | 0 | 0 | 24 | 9 | 3 | 3.79 |
| SP | Sabathia, C.Sabathia, CC >> | 28 | 2008 | L | 60 | 35 | 34 | 14 | 9 | 5.58 | .337 | 1.49 | 10.0 | 3.4 | 6.7 | 213.0 | 236 | 134 | 132 | 37 | 81 | 159 | 4 | 0 | 0 | 1 | 12 | 8 | 5 | 5.02 |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 45 | 33 | 33 | 9 | 14 | 5.24 | .338 | 1.51 | 11.2 | 2.4 | 6.2 | 211.1 | 263 | 133 | 123 | 34 | 57 | 146 | 2 | 0 | 0 | 1 | 11 | 4 | 5 | 4.58 |
| RP | Soriano, R.Soriano, Rafael † >> | 24 | 2003 | R | 97 | 109 | 0 | 11 | 4 | 3.12 | .268 | 1.05 | 7.0 | 2.4 | 9.9 | 170.0 | 133 | 60 | 59 | 17 | 46 | 187 | 0 | 16 | 3 | 0 | 0 | 8 | 0 | 3.05 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 80 | 91 | 0 | 2 | 10 | 5.28 | .312 | 1.34 | 7.3 | 4.8 | 9.0 | 102.1 | 83 | 60 | 60 | 15 | 54 | 102 | 0 | 7 | 7 | 0 | 0 | 2 | 4 | 4.56 |
| RP | Mantei, M.Mantei, Matt >> | 30 | 2003 | R | 60 | 79 | 0 | 5 | 0 | 3.15 | .307 | 1.29 | 8.0 | 3.6 | 9.5 | 97.0 | 86 | 38 | 34 | 11 | 39 | 102 | 0 | 4 | 6 | 0 | 0 | 4 | 1 | 3.70 |
| RP | Masset, N.Masset, Nick >> | 27 | 2009 | R | 45 | 71 | 0 | 5 | 2 | 1.83 | .260 | 1.03 | 6.3 | 3.0 | 8.2 | 78.2 | 55 | 18 | 16 | 8 | 26 | 71 | 0 | 3 | 3 | 0 | 0 | 2 | 2 | 3.59 |
| RP | Remlinger, M.Remlinger, Mike >> | 36 | 2002 | L | 35 | 58 | 0 | 6 | 8 | 4.09 | .338 | 1.47 | 9.5 | 3.7 | 8.6 | 66.0 | 70 | 32 | 30 | 8 | 27 | 63 | 0 | 4 | 2 | 0 | 0 | 4 | 0 | 4.08 |