| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 99 | 36 | 36 | 15 | 14 | 4.33 | .304 | 1.28 | 8.6 | 3.0 | 9.6 | 259.2 | 248 | 140 | 125 | 33 | 85 | 275 | 10 | 0 | 0 | 0 | 20 | 8 | 8 | 3.61 |
| SP | Duchscherer, J.Duchscherer, Justin >> | 31 | 2008 | R | 84 | 36 | 36 | 14 | 8 | 3.42 | .290 | 1.21 | 7.9 | 3.0 | 7.1 | 242.0 | 213 | 95 | 92 | 22 | 81 | 191 | 0 | 0 | 0 | 0 | 24 | 3 | 3 | 3.64 |
| SP | Williams, W.Williams, Woody † # >> | 36 | 2002 | R | 78 | 34 | 34 | 20 | 8 | 3.70 | .293 | 1.20 | 8.8 | 2.0 | 7.4 | 226.0 | 221 | 100 | 93 | 32 | 51 | 185 | 1 | 0 | 0 | 0 | 18 | 9 | 0 | 4.00 |
| SP | Nolasco, R.Nolasco, Ricky >> | 26 | 2008 | R | 55 | 29 | 29 | 4 | 13 | 6.08 | .333 | 1.46 | 10.6 | 2.6 | 7.1 | 171.2 | 202 | 119 | 116 | 34 | 49 | 134 | 1 | 0 | 0 | 0 | 12 | 6 | 1 | 4.98 |
| RP | Percival, T.Percival, Troy >> | 38 | 2007 | R | 84 | 80 | 0 | 8 | 2 | 2.82 | .269 | 1.09 | 6.7 | 3.2 | 6.9 | 108.2 | 80 | 37 | 34 | 11 | 38 | 83 | 0 | 9 | 4 | 0 | 0 | 2 | 4 | 3.90 |
| RP | Mota, G.Mota, Guillermo >> | 30 | 2003 | R | 49 | 51 | 0 | 5 | 9 | 5.43 | .331 | 1.43 | 9.0 | 4.0 | 5.9 | 61.1 | 61 | 40 | 37 | 15 | 27 | 40 | 0 | 8 | 5 | 0 | 0 | 3 | 0 | 6.36 |
| RP | Hawkins, L.Hawkins, LaTroy >> | 30 | 2002 | R | 40 | 48 | 0 | 2 | 1 | 2.60 | .278 | 1.14 | 7.5 | 2.8 | 8.0 | 55.1 | 46 | 20 | 16 | 9 | 17 | 49 | 0 | 4 | 1 | 0 | 0 | 1 | 2 | 4.33 |
| SP | Kazmir, S.Kazmir, Scott >> | 24 | 2008 | L | 40 | 4 | 3 | 0 | 0 | 5.59 | .333 | 1.50 | 8.5 | 5.2 | 9.9 | 19.1 | 18 | 12 | 12 | 2 | 11 | 21 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 3.89 |
| SP | Burkett, J.Burkett, John >> | 37 | 2001 | R | 49 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Willis, D.Willis, Dontrelle >> | 23 | 2005 | L | 47 | 15 | 0 | 3 | 3 | 2.25 | .326 | 1.35 | 9.5 | 2.7 | 4.5 | 20.0 | 21 | 6 | 5 | 2 | 6 | 10 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 4.50 |