| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 30 | 30 | 14 | 10 | 4.20 | .291 | 1.20 | 8.6 | 2.3 | 5.3 | 203.1 | 194 | 97 | 95 | 24 | 51 | 119 | 2 | 0 | 0 | 0 | 17 | 5 | 8 | 4.19 |
| SP | Sutton, D.Sutton, Don # >> | 27 | 1972 | R | 82 | 29 | 29 | 14 | 10 | 3.64 | .280 | 1.13 | 7.8 | 2.5 | 4.8 | 212.2 | 183 | 87 | 86 | 13 | 58 | 114 | 5 | 0 | 0 | 1 | 15 | 7 | 2 | 3.64 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 76 | 29 | 29 | 14 | 10 | 3.80 | .290 | 1.19 | 8.1 | 2.7 | 5.3 | 220.1 | 198 | 94 | 93 | 21 | 65 | 130 | 7 | 0 | 0 | 1 | 16 | 7 | 1 | 4.04 |
| CL | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 68 | 0 | 5 | 10 | 3.07 | .261 | 1.06 | 6.0 | 3.6 | 9.4 | 76.1 | 51 | 26 | 26 | 9 | 30 | 79 | 0 | 46 | 3 | 0 | 0 | 0 | 0 | 3.64 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 57 | 0 | 1 | 0 | 2.86 | .304 | 1.28 | 6.5 | 5.1 | 8.5 | 69.1 | 50 | 25 | 22 | 6 | 39 | 65 | 0 | 1 | 2 | 0 | 0 | 2 | 3 | 4.03 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 46 | 0 | 5 | 3 | 3.99 | .297 | 1.25 | 6.9 | 4.4 | 9.4 | 47.1 | 36 | 21 | 21 | 6 | 23 | 49 | 0 | 2 | 1 | 0 | 0 | 1 | 8 | 4.11 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 22 | 0 | 3 | 0 | 3.60 | .286 | 1.16 | 5.4 | 5.0 | 7.6 | 25.0 | 15 | 10 | 10 | 4 | 14 | 21 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 5.20 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 66 | 16 | 0 | 0 | 2 | 4.60 | .277 | 1.15 | 7.8 | 3.0 | 6.0 | 15.2 | 13 | 8 | 8 | 3 | 5 | 10 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.27 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 3 | 0 | 2 | 0 | 3.52 | .395 | 1.96 | 14.1 | 5.1 | 7.7 | 7.2 | 11 | 3 | 3 | 0 | 4 | 6 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.00 |