| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 15 | 15 | 6 | 7 | 4.50 | .310 | 1.29 | 9.2 | 2.4 | 8.6 | 92.0 | 94 | 46 | 46 | 11 | 25 | 88 | 0 | 0 | 0 | 0 | 10 | 5 | 0 | 3.62 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 15 | 15 | 4 | 7 | 5.21 | .328 | 1.45 | 10.0 | 3.1 | 8.1 | 103.2 | 114 | 61 | 60 | 11 | 36 | 93 | 1 | 0 | 0 | 0 | 4 | 2 | 3 | 3.69 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 14 | 14 | 4 | 8 | 6.24 | .321 | 1.41 | 9.6 | 3.1 | 4.2 | 88.0 | 94 | 63 | 61 | 15 | 30 | 41 | 2 | 0 | 0 | 1 | 4 | 1 | 2 | 5.34 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 29 | 0 | 2 | 2 | 2.73 | .226 | 0.84 | 5.6 | 2.2 | 11.5 | 29.2 | 18 | 9 | 9 | 3 | 7 | 37 | 0 | 20 | 2 | 0 | 0 | 1 | 0 | 2.62 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 93 | 37 | 0 | 3 | 0 | 2.93 | .345 | 1.51 | 8.4 | 5.2 | 8.6 | 43.0 | 40 | 14 | 14 | 3 | 25 | 41 | 0 | 0 | 1 | 0 | 0 | 3 | 0 | 3.95 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 83 | 31 | 0 | 1 | 0 | 4.37 | .331 | 1.46 | 9.0 | 4.1 | 5.4 | 35.0 | 35 | 17 | 17 | 4 | 16 | 21 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.74 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 20 | 0 | 1 | 1 | 4.24 | .271 | 1.11 | 5.9 | 4.3 | 7.0 | 23.1 | 15 | 11 | 11 | 1 | 11 | 18 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.43 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 12 | 0 | 0 | 2 | 3.38 | .216 | 0.83 | 4.8 | 2.8 | 9.0 | 13.1 | 7 | 5 | 5 | 2 | 4 | 13 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.92 |