| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 15 | 15 | 9 | 2 | 3.19 | .259 | 1.00 | 7.2 | 1.9 | 4.4 | 115.2 | 92 | 41 | 41 | 6 | 24 | 56 | 6 | 0 | 0 | 2 | 11 | 5 | 3 | 3.46 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 14 | 14 | 10 | 2 | 2.48 | .232 | 0.90 | 7.0 | 1.1 | 4.1 | 109.0 | 85 | 31 | 30 | 8 | 13 | 50 | 5 | 0 | 0 | 1 | 12 | 1 | 0 | 3.42 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 81 | 14 | 14 | 4 | 5 | 5.18 | .322 | 1.39 | 9.3 | 3.2 | 5.1 | 92.0 | 95 | 53 | 53 | 19 | 33 | 52 | 2 | 0 | 0 | 1 | 5 | 3 | 0 | 5.73 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 14 | 14 | 6 | 7 | 4.99 | .313 | 1.35 | 9.4 | 2.7 | 7.1 | 92.0 | 96 | 51 | 51 | 15 | 28 | 73 | 1 | 0 | 0 | 0 | 6 | 2 | 0 | 4.51 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 32 | 0 | 1 | 1 | 3.09 | .238 | 0.94 | 6.2 | 2.3 | 8.4 | 32.0 | 22 | 12 | 11 | 2 | 8 | 30 | 0 | 24 | 3 | 0 | 0 | 0 | 0 | 2.69 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 85 | 31 | 0 | 3 | 0 | 2.70 | .271 | 1.07 | 5.9 | 3.9 | 5.5 | 23.1 | 15 | 8 | 7 | 5 | 10 | 14 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 6.04 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 20 | 0 | 0 | 0 | 2.35 | .281 | 1.17 | 7.2 | 3.6 | 8.4 | 15.1 | 12 | 4 | 4 | 0 | 6 | 14 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.33 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 22 | 0 | 0 | 1 | 4.20 | .297 | 1.20 | 7.8 | 3.0 | 9.6 | 15.0 | 13 | 8 | 7 | 1 | 5 | 16 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2.93 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 4 | 1 | 1 | 0 | 5.68 | .329 | 1.47 | 9.9 | 3.3 | 7.6 | 19.0 | 21 | 14 | 12 | 2 | 7 | 16 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 3.79 |