| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 15 | 15 | 5 | 8 | 3.73 | .274 | 1.11 | 8.1 | 1.9 | 8.8 | 118.1 | 106 | 52 | 49 | 15 | 25 | 115 | 5 | 0 | 0 | 1 | 9 | 3 | 3 | 3.42 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 15 | 15 | 5 | 8 | 4.09 | .322 | 1.41 | 8.8 | 3.9 | 4.3 | 114.1 | 111 | 56 | 52 | 12 | 50 | 55 | 7 | 0 | 0 | 0 | 7 | 2 | 2 | 4.77 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 14 | 14 | 5 | 5 | 4.44 | .322 | 1.41 | 8.2 | 4.5 | 4.0 | 95.1 | 87 | 48 | 47 | 13 | 47 | 42 | 2 | 0 | 0 | 0 | 7 | 2 | 1 | 5.44 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 36 | 0 | 1 | 3 | 2.57 | .250 | 1.00 | 5.4 | 3.6 | 9.4 | 42.0 | 25 | 13 | 12 | 4 | 17 | 44 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.36 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 25 | 0 | 1 | 1 | 1.59 | .267 | 1.06 | 9.0 | 0.6 | 9.6 | 28.1 | 28 | 6 | 5 | 2 | 2 | 30 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 2.11 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 65 | 19 | 0 | 3 | 2 | 6.75 | .348 | 1.60 | 11.7 | 2.7 | 6.8 | 20.0 | 26 | 15 | 15 | 6 | 6 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.30 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 57 | 14 | 0 | 0 | 0 | 2.70 | .296 | 1.26 | 8.4 | 3.4 | 8.4 | 16.2 | 15 | 6 | 5 | 2 | 6 | 15 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 3.88 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 1 | 0 | 0 | 0 | 15.00 | .526 | 3.33 | 21.0 | 9.0 | 9.0 | 3.0 | 7 | 5 | 5 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.00 |