| SP | Kluber, C.Kluber, Corey # >> | 32 | 2018 | R | 91 | 31 | 31 | 14 | 7 | 3.55 | .313 | 1.31 | 9.5 | 2.4 | 10.0 | 205.1 | 216 | 84 | 81 | 14 | 54 | 227 | 1 | 0 | 0 | 0 | 20 | 10 | 4 | 2.61 |
| SP | Morton, C.Morton, Charlie # >> | 35 | 2018 | R | 86 | 30 | 30 | 6 | 15 | 6.64 | .359 | 1.65 | 11.0 | 3.9 | 9.8 | 146.1 | 178 | 113 | 108 | 34 | 64 | 159 | 0 | 0 | 0 | 0 | 10 | 4 | 2 | 5.25 |
| SP | Clevinger, M.Clevinger, Mike >> | 27 | 2018 | R | 81 | 30 | 30 | 17 | 6 | 4.94 | .334 | 1.49 | 9.8 | 3.7 | 9.5 | 178.2 | 193 | 99 | 98 | 24 | 74 | 188 | 0 | 0 | 0 | 0 | 15 | 2 | 4 | 3.92 |
| SP | Chacin, J.Chacin, Jhoulys >> | 30 | 2018 | R | 78 | 29 | 29 | 12 | 9 | 4.64 | .338 | 1.50 | 9.2 | 4.3 | 7.2 | 153.1 | 157 | 84 | 79 | 22 | 73 | 122 | 0 | 0 | 0 | 0 | 10 | 5 | 0 | 4.80 |
| RP | Osuna, R.Osuna, Roberto >> | 23 | 2018 | R | 72 | 56 | 0 | 3 | 1 | 5.53 | .348 | 1.49 | 11.4 | 2.2 | 7.6 | 53.2 | 67 | 34 | 33 | 7 | 13 | 45 | 0 | 3 | 0 | 0 | 0 | 6 | 5 | 4.09 |
| CL | Leclerc, J.Leclerc, Jose † >> | 24 | 2018 | R | 99 | 70 | 0 | 2 | 3 | 2.36 | .302 | 1.27 | 6.0 | 5.5 | 10.0 | 72.1 | 48 | 20 | 19 | 2 | 44 | 80 | 0 | 37 | 4 | 0 | 0 | 2 | 0 | 3.06 |
| SP | Wacha, M.Wacha, Michael >> | 26 | 2018 | R | 70 | 21 | 0 | 6 | 1 | 4.50 | .378 | 1.79 | 8.0 | 8.0 | 9.3 | 28.0 | 25 | 15 | 14 | 5 | 25 | 29 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 6.04 |