| SP | Verlander, J.Verlander, Justin † >> | 35 | 2018 | R | 98 | 30 | 30 | 16 | 10 | 3.99 | .297 | 1.21 | 8.1 | 2.8 | 10.0 | 196.1 | 177 | 88 | 87 | 24 | 61 | 218 | 1 | 0 | 0 | 1 | 17 | 11 | 4 | 3.47 |
| SP | Paxton, J.Paxton, James # >> | 29 | 2018 | L | 89 | 30 | 30 | 7 | 14 | 5.23 | .331 | 1.44 | 9.5 | 3.4 | 10.5 | 165.1 | 175 | 98 | 96 | 28 | 63 | 192 | 0 | 0 | 0 | 0 | 11 | 7 | 12 | 4.15 |
| SP | Greinke, Z.Greinke, Zack # >> | 35 | 2018 | R | 84 | 29 | 29 | 7 | 11 | 5.14 | .334 | 1.46 | 9.6 | 3.6 | 8.8 | 177.0 | 189 | 105 | 101 | 30 | 70 | 174 | 0 | 0 | 0 | 0 | 12 | 7 | 4 | 4.54 |
| SP | Cahill, T.Cahill, Trevor >> | 30 | 2018 | R | 72 | 30 | 29 | 5 | 11 | 6.70 | .357 | 1.64 | 10.4 | 4.4 | 7.7 | 143.2 | 165 | 108 | 107 | 26 | 70 | 123 | 0 | 0 | 0 | 0 | 6 | 4 | 11 | 5.20 |
| SP | Jackson, E.Jackson, Edwin >> | 35 | 2018 | R | 67 | 29 | 28 | 8 | 6 | 5.89 | .368 | 1.71 | 10.4 | 5.0 | 7.0 | 133.0 | 153 | 93 | 87 | 18 | 74 | 103 | 0 | 1 | 0 | 0 | 4 | 5 | 5 | 4.99 |
| RP | Chapman, A.Chapman, Aroldis >> | 30 | 2018 | L | 92 | 88 | 0 | 8 | 5 | 3.88 | .310 | 1.32 | 5.9 | 6.0 | 12.0 | 111.1 | 73 | 50 | 48 | 9 | 74 | 148 | 0 | 2 | 3 | 0 | 0 | 3 | 9 | 3.47 |
| RP | Rogers, T.Rogers, Taylor >> | 27 | 2018 | L | 90 | 74 | 0 | 4 | 5 | 2.84 | .280 | 1.13 | 8.3 | 2.0 | 10.4 | 101.1 | 93 | 35 | 32 | 9 | 22 | 117 | 0 | 1 | 4 | 0 | 0 | 3 | 0 | 2.58 |
| RP | Stammen, C.Stammen, Craig >> | 34 | 2018 | R | 74 | 62 | 0 | 4 | 2 | 3.68 | .323 | 1.38 | 9.1 | 3.3 | 9.5 | 73.1 | 74 | 30 | 30 | 5 | 27 | 77 | 0 | 2 | 0 | 0 | 0 | 4 | 2 | 3.05 |
| RP | Harris, W.Harris, Will >> | 33 | 2018 | R | 66 | 51 | 0 | 3 | 3 | 3.30 | .333 | 1.47 | 9.5 | 3.8 | 11.8 | 57.1 | 60 | 21 | 21 | 4 | 24 | 75 | 0 | 2 | 1 | 0 | 0 | 2 | 5 | 2.65 |
| CL | McHugh, C.McHugh, Collin † >> | 31 | 2018 | R | 96 | 62 | 0 | 6 | 2 | 1.92 | .285 | 1.15 | 7.2 | 3.2 | 11.1 | 70.1 | 56 | 16 | 15 | 6 | 25 | 86 | 0 | 28 | 1 | 0 | 0 | 3 | 0 | 2.86 |