| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 36 | 36 | 15 | 9 | 3.74 | .312 | 1.33 | 9.2 | 2.7 | 7.6 | 253.0 | 259 | 111 | 105 | 18 | 77 | 215 | 3 | 0 | 0 | 0 | 25 | 8 | 3 | 3.23 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 35 | 35 | 9 | 14 | 4.44 | .324 | 1.42 | 7.5 | 5.3 | 8.1 | 216.2 | 180 | 116 | 107 | 16 | 128 | 195 | 0 | 0 | 0 | 0 | 19 | 4 | 4 | 3.99 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 79 | 33 | 33 | 10 | 10 | 4.65 | .329 | 1.46 | 10.2 | 3.0 | 8.1 | 191.2 | 216 | 101 | 99 | 23 | 64 | 172 | 0 | 0 | 0 | 0 | 17 | 2 | 6 | 3.80 |
| SP | McGinnity, J.McGinnity, Joe # >> | 33 | 1904 | R | 50 | 34 | 33 | 15 | 12 | 5.06 | .332 | 1.46 | 10.0 | 3.2 | 4.1 | 222.1 | 247 | 128 | 125 | 22 | 78 | 101 | 6 | 0 | 0 | 1 | 15 | 7 | 2 | 4.53 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 100 | 0 | 10 | 5 | 3.47 | .291 | 1.21 | 6.9 | 4.0 | 6.9 | 109.0 | 84 | 47 | 42 | 15 | 48 | 83 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 4.64 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 69 | 0 | 6 | 3 | 3.42 | .326 | 1.41 | 8.1 | 4.7 | 9.6 | 76.1 | 68 | 31 | 29 | 9 | 40 | 81 | 0 | 0 | 0 | 0 | 0 | 3 | 8 | 4.11 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 65 | 0 | 8 | 5 | 3.63 | .301 | 1.28 | 8.8 | 2.8 | 7.7 | 74.1 | 72 | 32 | 30 | 7 | 23 | 63 | 0 | 0 | 3 | 0 | 0 | 1 | 0 | 3.50 |
| SU | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 93 | 87 | 0 | 4 | 8 | 3.93 | .324 | 1.42 | 7.2 | 5.7 | 9.9 | 100.2 | 80 | 44 | 44 | 8 | 63 | 110 | 0 | 1 | 5 | 0 | 0 | 2 | 7 | 3.79 |
| CL | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 87 | 86 | 0 | 0 | 4 | 2.95 | .268 | 1.10 | 8.4 | 1.5 | 8.6 | 88.1 | 82 | 29 | 29 | 6 | 15 | 84 | 0 | 50 | 7 | 0 | 0 | 0 | 0 | 2.49 |