| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 11 | 11 | 1 | 7 | 4.57 | .298 | 1.25 | 8.7 | 2.5 | 8.5 | 69.0 | 67 | 35 | 35 | 8 | 19 | 65 | 2 | 0 | 0 | 0 | 7 | 2 | 3 | 3.54 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 11 | 11 | 2 | 3 | 4.44 | .317 | 1.38 | 9.7 | 2.7 | 4.9 | 79.0 | 85 | 49 | 39 | 11 | 24 | 43 | 2 | 0 | 0 | 1 | 4 | 1 | 1 | 4.67 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 11 | 11 | 3 | 7 | 6.21 | .381 | 1.83 | 12.9 | 3.6 | 5.4 | 62.1 | 89 | 44 | 43 | 8 | 25 | 37 | 0 | 0 | 0 | 0 | 3 | 1 | 1 | 4.74 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 10 | 10 | 2 | 7 | 6.99 | .347 | 1.57 | 9.4 | 5.0 | 7.7 | 47.2 | 49 | 37 | 37 | 9 | 26 | 40 | 0 | 0 | 0 | 0 | 4 | 1 | 2 | 5.51 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 27 | 0 | 2 | 3 | 3.76 | .303 | 1.30 | 7.1 | 4.7 | 10.4 | 38.1 | 30 | 19 | 16 | 4 | 20 | 44 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 3.63 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 26 | 0 | 3 | 1 | 4.65 | .256 | 1.03 | 7.7 | 1.8 | 9.0 | 40.2 | 34 | 22 | 21 | 6 | 8 | 40 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 3.55 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 57 | 24 | 0 | 1 | 1 | 3.21 | .306 | 1.29 | 8.0 | 3.5 | 8.7 | 28.0 | 25 | 10 | 10 | 4 | 11 | 27 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.21 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 49 | 21 | 0 | 0 | 0 | 4.86 | .366 | 1.70 | 8.8 | 6.6 | 6.8 | 37.0 | 36 | 20 | 20 | 7 | 27 | 28 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 6.22 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 56 | 1 | 1 | 0 | 1 | 12.46 | .458 | 2.54 | 18.0 | 6.8 | 6.8 | 4.1 | 8 | 6 | 6 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.75 |
| SP | McQuillan, G.McQuillan, George >> | 23 | 1908 | R | 48 | 14 | 0 | 3 | 2 | 5.34 | .311 | 1.35 | 9.3 | 3.0 | 5.7 | 30.1 | 31 | 21 | 18 | 5 | 10 | 19 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.90 |