| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 15 | 15 | 5 | 10 | 3.74 | .273 | 1.11 | 7.4 | 2.5 | 4.9 | 113.0 | 93 | 52 | 47 | 19 | 32 | 62 | 5 | 0 | 0 | 1 | 10 | 2 | 4 | 4.99 |
| SP | Maddux, G.Maddux, Greg # >> | 29 | 1995 | R | 89 | 14 | 14 | 7 | 3 | 4.41 | .287 | 1.17 | 9.0 | 1.5 | 5.6 | 100.0 | 100 | 51 | 49 | 12 | 17 | 62 | 4 | 0 | 0 | 1 | 8 | 4 | 1 | 3.95 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 39 | 0 | 2 | 0 | 2.59 | .266 | 1.07 | 7.5 | 2.3 | 10.5 | 48.2 | 40 | 14 | 14 | 5 | 12 | 56 | 0 | 5 | 0 | 0 | 0 | 1 | 1 | 2.83 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 25 | 0 | 1 | 0 | 2.12 | .305 | 1.31 | 6.8 | 5.3 | 4.7 | 29.2 | 22 | 7 | 7 | 1 | 17 | 15 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 4.17 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 59 | 19 | 0 | 1 | 0 | 4.50 | .333 | 1.50 | 8.0 | 5.5 | 9.5 | 18.0 | 16 | 9 | 9 | 1 | 11 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.44 |
| RP | Hernandez, W.Hernandez, Willie >> | 30 | 1984 | L | 44 | 12 | 0 | 2 | 0 | 3.07 | .267 | 1.09 | 7.1 | 3.2 | 5.8 | 14.2 | 11 | 5 | 5 | 2 | 5 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.64 |
| SP | Chance, D.Chance, Dean >> | 23 | 1964 | R | 53 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Coombs, J.Coombs, Jack >> | 28 | 1910 | R | 45 | 1 | 0 | 0 | 0 | 6.75 | .500 | 3.00 | 27.0 | 9.0 | 0.0 | 1.1 | 3 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 19.00 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 8 | 0 | 1 | 2 | 6.19 | .342 | 1.56 | 11.3 | 2.8 | 5.6 | 16.0 | 20 | 11 | 11 | 4 | 5 | 10 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.94 |