| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 15 | 15 | 4 | 7 | 4.27 | .291 | 1.21 | 7.6 | 3.3 | 8.9 | 92.2 | 78 | 46 | 44 | 11 | 34 | 91 | 2 | 0 | 0 | 1 | 8 | 2 | 0 | 3.75 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 14 | 14 | 5 | 5 | 5.32 | .344 | 1.56 | 10.3 | 3.9 | 5.3 | 86.1 | 98 | 54 | 51 | 10 | 37 | 51 | 1 | 0 | 0 | 0 | 4 | 1 | 3 | 4.65 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 34 | 0 | 3 | 2 | 6.09 | .358 | 1.65 | 9.0 | 5.8 | 11.6 | 34.0 | 34 | 23 | 23 | 7 | 22 | 44 | 0 | 0 | 2 | 0 | 0 | 1 | 1 | 5.12 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 30 | 0 | 1 | 4 | 3.12 | .307 | 1.33 | 8.7 | 3.4 | 5.3 | 34.2 | 33 | 13 | 12 | 4 | 13 | 20 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.50 |
| CL | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 33 | 0 | 1 | 1 | 2.43 | .265 | 1.08 | 7.1 | 2.7 | 7.6 | 33.1 | 26 | 9 | 9 | 3 | 10 | 28 | 0 | 19 | 1 | 0 | 0 | 0 | 3 | 3.39 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 8 | 0 | 1 | 1 | 4.30 | .333 | 1.36 | 9.6 | 3.2 | 3.9 | 14.2 | 15 | 7 | 7 | 4 | 5 | 6 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 7.36 |