| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 11 | 11 | 5 | 3 | 3.96 | .269 | 1.09 | 8.4 | 1.4 | 7.4 | 75.0 | 70 | 33 | 33 | 8 | 12 | 62 | 3 | 0 | 0 | 1 | 8 | 1 | 3 | 3.25 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 11 | 11 | 5 | 6 | 4.75 | .310 | 1.35 | 8.6 | 3.5 | 9.6 | 72.0 | 69 | 40 | 38 | 10 | 28 | 77 | 2 | 0 | 0 | 1 | 5 | 0 | 1 | 3.83 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 11 | 11 | 5 | 0 | 3.31 | .299 | 1.26 | 7.5 | 3.8 | 8.3 | 68.0 | 57 | 27 | 25 | 8 | 29 | 63 | 0 | 0 | 0 | 0 | 5 | 1 | 2 | 4.00 |
| SP | Gooden, D.Gooden, Dwight # >> | 21 | 1985 | R | 68 | 11 | 11 | 4 | 4 | 6.10 | .320 | 1.38 | 9.4 | 3.1 | 6.7 | 69.1 | 72 | 48 | 47 | 10 | 24 | 51 | 1 | 0 | 0 | 1 | 3 | 2 | 2 | 4.54 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 25 | 0 | 1 | 0 | 4.03 | .331 | 1.45 | 7.1 | 5.9 | 11.5 | 29.0 | 23 | 13 | 13 | 6 | 19 | 37 | 0 | 4 | 4 | 0 | 0 | 1 | 3 | 5.21 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 24 | 0 | 2 | 2 | 4.44 | .331 | 1.41 | 8.7 | 4.2 | 8.7 | 26.1 | 25 | 15 | 13 | 4 | 12 | 25 | 0 | 1 | 2 | 0 | 0 | 2 | 0 | 4.69 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 15 | 0 | 1 | 1 | 2.65 | .239 | 0.88 | 5.3 | 2.6 | 7.4 | 17.0 | 10 | 5 | 5 | 3 | 5 | 14 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 4.71 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 14 | 0 | 1 | 1 | 1.35 | .268 | 1.05 | 7.2 | 2.3 | 7.7 | 20.0 | 16 | 3 | 3 | 1 | 5 | 17 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 2.85 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 11 | 0 | 0 | 1 | 6.23 | .391 | 1.92 | 13.2 | 4.2 | 10.4 | 13.0 | 19 | 9 | 9 | 1 | 6 | 15 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.08 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 24 | 0 | 0 | 6 | 6.14 | .328 | 1.47 | 8.1 | 5.3 | 8.7 | 29.1 | 26 | 23 | 20 | 5 | 17 | 28 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 5.07 |