| SP | Verlander, J.Verlander, Justin † >> | 36 | 2019 | R | 99 | 36 | 36 | 16 | 13 | 4.33 | .286 | 1.17 | 8.6 | 1.9 | 8.7 | 268.1 | 256 | 135 | 129 | 34 | 57 | 258 | 7 | 0 | 0 | 0 | 19 | 9 | 5 | 3.46 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 34 | 34 | 7 | 15 | 5.60 | .322 | 1.41 | 9.1 | 3.6 | 8.2 | 205.2 | 208 | 129 | 128 | 37 | 81 | 187 | 4 | 0 | 0 | 0 | 15 | 4 | 6 | 4.77 |
| SP | Johnson, R.Johnson, Randy † >> | 41 | 2004 | L | 84 | 33 | 33 | 15 | 12 | 3.64 | .280 | 1.13 | 7.6 | 2.6 | 8.5 | 227.2 | 192 | 93 | 92 | 28 | 66 | 214 | 8 | 0 | 0 | 2 | 24 | 8 | 1 | 3.70 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 84 | 31 | 31 | 8 | 11 | 5.26 | .324 | 1.42 | 10.4 | 2.4 | 4.9 | 176.1 | 204 | 104 | 103 | 26 | 47 | 95 | 0 | 0 | 0 | 0 | 12 | 3 | 5 | 4.69 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 41 | 0 | 2 | 3 | 3.60 | .312 | 1.34 | 7.7 | 4.3 | 4.1 | 50.0 | 43 | 23 | 20 | 3 | 24 | 23 | 0 | 6 | 2 | 0 | 0 | 1 | 2 | 4.36 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 39 | 0 | 3 | 3 | 3.22 | .323 | 1.41 | 9.0 | 3.9 | 7.8 | 44.2 | 44 | 18 | 16 | 3 | 19 | 38 | 0 | 9 | 1 | 0 | 0 | 1 | 0 | 3.52 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 78 | 24 | 0 | 1 | 2 | 7.11 | .387 | 1.86 | 10.8 | 6.1 | 8.6 | 25.1 | 30 | 20 | 20 | 4 | 17 | 24 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 5.32 |
| CL | Uehara, K.Uehara, Koji # >> | 38 | 2013 | R | 100 | 67 | 0 | 5 | 6 | 4.28 | .309 | 1.30 | 8.3 | 3.4 | 8.7 | 94.2 | 87 | 47 | 45 | 9 | 36 | 91 | 0 | 4 | 8 | 0 | 0 | 4 | 1 | 3.59 |