| SP | Koufax, S.Koufax, Sandy † >> | 30 | 1965 | L | 97 | 27 | 27 | 15 | 8 | 3.34 | .275 | 1.12 | 7.6 | 2.5 | 7.6 | 183.0 | 155 | 68 | 68 | 19 | 50 | 155 | 1 | 0 | 0 | 0 | 19 | 3 | 1 | 3.52 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 26 | 26 | 11 | 12 | 4.47 | .303 | 1.29 | 8.8 | 2.8 | 7.3 | 173.1 | 170 | 90 | 86 | 24 | 53 | 140 | 2 | 0 | 0 | 0 | 13 | 3 | 3 | 4.16 |
| SP | Guidry, R.Guidry, Ron # >> | 28 | 1978 | L | 77 | 26 | 26 | 10 | 11 | 4.52 | .308 | 1.30 | 8.8 | 3.0 | 5.6 | 183.0 | 178 | 107 | 92 | 17 | 60 | 113 | 6 | 0 | 0 | 2 | 14 | 6 | 3 | 4.05 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 25 | 25 | 15 | 4 | 3.40 | .293 | 1.24 | 7.4 | 3.8 | 4.4 | 172.0 | 141 | 68 | 65 | 12 | 73 | 85 | 1 | 0 | 0 | 0 | 16 | 0 | 2 | 4.19 |
| CL | Wagner, B.Wagner, Billy † >> | 28 | 1999 | L | 95 | 49 | 0 | 0 | 5 | 2.26 | .261 | 1.06 | 5.7 | 3.9 | 8.0 | 55.2 | 35 | 14 | 14 | 6 | 24 | 49 | 0 | 33 | 6 | 0 | 0 | 0 | 3 | 3.95 |
| SU | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 43 | 0 | 0 | 3 | 3.22 | .221 | 0.85 | 5.3 | 2.5 | 8.2 | 44.2 | 26 | 16 | 16 | 2 | 12 | 40 | 0 | 3 | 4 | 0 | 0 | 0 | 2 | 2.59 |
| RP | Miller, A.Miller, Andrew † >> | 29 | 2014 | L | 88 | 61 | 0 | 6 | 1 | 2.54 | .230 | 0.90 | 6.3 | 1.9 | 9.1 | 63.2 | 44 | 19 | 18 | 8 | 13 | 64 | 0 | 2 | 2 | 0 | 0 | 0 | 4 | 3.24 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 34 | 0 | 5 | 0 | 2.54 | .264 | 1.08 | 6.9 | 2.8 | 7.4 | 39.0 | 30 | 12 | 11 | 3 | 12 | 32 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.28 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 65 | 22 | 0 | 1 | 0 | 2.21 | .208 | 0.79 | 5.0 | 2.3 | 7.2 | 20.1 | 11 | 5 | 5 | 2 | 5 | 16 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.45 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 14 | 0 | 0 | 2 | 3.38 | .259 | 0.98 | 6.2 | 2.8 | 9.0 | 13.1 | 9 | 5 | 5 | 3 | 4 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.15 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 51 | 4 | 0 | 0 | 0 | 2.70 | .286 | 1.20 | 9.0 | 3.0 | 9.0 | 3.1 | 3 | 1 | 1 | 1 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.33 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 53 | 7 | 0 | 0 | 0 | 5.79 | .300 | 1.29 | 7.0 | 5.0 | 6.0 | 9.1 | 7 | 6 | 6 | 3 | 5 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.67 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 39 | 6 | 0 | 0 | 0 | 2.96 | .287 | 1.21 | 8.3 | 2.7 | 8.7 | 27.1 | 25 | 9 | 9 | 1 | 8 | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 2.44 |