| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 15 | 15 | 7 | 6 | 5.04 | .305 | 1.32 | 9.5 | 2.4 | 10.1 | 105.1 | 111 | 59 | 59 | 12 | 28 | 118 | 1 | 0 | 0 | 0 | 7 | 0 | 3 | 3.04 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 14 | 14 | 6 | 7 | 3.47 | .291 | 1.21 | 5.2 | 5.7 | 8.5 | 96.0 | 55 | 39 | 37 | 10 | 61 | 91 | 2 | 0 | 0 | 1 | 8 | 2 | 2 | 4.43 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 14 | 14 | 3 | 5 | 4.48 | .326 | 1.42 | 9.8 | 3.1 | 4.9 | 72.1 | 78 | 39 | 36 | 10 | 25 | 39 | 0 | 0 | 0 | 0 | 3 | 2 | 0 | 4.85 |
| SP | Cueto, J.Cueto, Johnny # >> | 28 | 2014 | R | 75 | 14 | 14 | 9 | 2 | 3.53 | .300 | 1.26 | 8.0 | 3.3 | 6.7 | 97.0 | 86 | 42 | 38 | 10 | 36 | 72 | 1 | 0 | 0 | 0 | 8 | 3 | 4 | 4.06 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 15 | 14 | 5 | 5 | 7.93 | .365 | 1.71 | 11.5 | 3.9 | 6.4 | 76.0 | 97 | 69 | 67 | 25 | 33 | 54 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 7.20 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 42 | 0 | 3 | 0 | 2.85 | .211 | 0.78 | 5.9 | 1.2 | 9.7 | 53.2 | 35 | 18 | 17 | 6 | 7 | 57 | 0 | 8 | 1 | 0 | 0 | 1 | 2 | 2.77 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 36 | 0 | 2 | 3 | 1.54 | .198 | 0.72 | 4.3 | 2.3 | 8.7 | 52.2 | 25 | 9 | 9 | 3 | 13 | 50 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | 2.63 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 27 | 0 | 1 | 0 | 2.05 | .264 | 1.04 | 7.5 | 2.1 | 8.1 | 30.2 | 25 | 9 | 7 | 2 | 7 | 27 | 0 | 5 | 0 | 0 | 0 | 1 | 0 | 2.87 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 14 | 0 | 1 | 0 | 1.93 | .344 | 1.57 | 8.4 | 5.8 | 9.6 | 14.0 | 13 | 5 | 3 | 1 | 9 | 15 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.71 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 15 | 0 | 0 | 2 | 3.66 | .272 | 1.12 | 6.6 | 3.8 | 9.9 | 19.2 | 14 | 8 | 8 | 2 | 8 | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.42 |