| SP | Tiant, L.Tiant, Luis # >> | 28 | 1968 | R | 97 | 27 | 27 | 13 | 10 | 3.26 | .263 | 1.05 | 7.0 | 2.5 | 7.9 | 204.1 | 158 | 75 | 74 | 19 | 56 | 180 | 13 | 0 | 0 | 2 | 17 | 5 | 4 | 3.34 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 26 | 26 | 12 | 10 | 4.47 | .302 | 1.27 | 8.6 | 2.9 | 7.7 | 169.0 | 161 | 91 | 84 | 20 | 54 | 144 | 1 | 0 | 0 | 0 | 16 | 4 | 1 | 3.86 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 26 | 26 | 8 | 11 | 4.76 | .323 | 1.41 | 9.0 | 3.7 | 5.0 | 187.0 | 187 | 112 | 99 | 26 | 76 | 103 | 8 | 0 | 0 | 0 | 9 | 5 | 3 | 5.01 |
| SP | Gooden, D.Gooden, Dwight # >> | 21 | 1985 | R | 67 | 26 | 26 | 4 | 12 | 5.50 | .337 | 1.48 | 9.9 | 3.5 | 6.4 | 168.2 | 185 | 112 | 103 | 26 | 65 | 120 | 4 | 0 | 0 | 1 | 10 | 7 | 4 | 4.87 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 63 | 25 | 25 | 8 | 14 | 4.65 | .323 | 1.42 | 9.5 | 3.4 | 4.8 | 153.0 | 161 | 83 | 79 | 17 | 57 | 82 | 0 | 0 | 0 | 0 | 13 | 1 | 4 | 4.51 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 68 | 0 | 6 | 5 | 3.64 | .282 | 1.17 | 8.1 | 2.4 | 9.0 | 89.0 | 80 | 40 | 36 | 10 | 24 | 89 | 0 | 14 | 1 | 0 | 0 | 1 | 1 | 3.30 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 52 | 0 | 4 | 2 | 2.12 | .268 | 1.08 | 6.0 | 3.9 | 5.0 | 63.2 | 42 | 17 | 15 | 3 | 27 | 35 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 3.84 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 37 | 0 | 4 | 0 | 3.38 | .327 | 1.43 | 8.8 | 4.2 | 6.2 | 45.1 | 44 | 27 | 17 | 5 | 21 | 31 | 0 | 6 | 0 | 0 | 0 | 1 | 0 | 4.53 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 25 | 0 | 0 | 1 | 4.22 | .319 | 1.39 | 7.5 | 5.0 | 4.6 | 49.0 | 41 | 25 | 23 | 4 | 27 | 25 | 0 | 3 | 0 | 0 | 0 | 1 | 1 | 4.76 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 58 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 2 | 0 | 0 | 0 | 0.00 | .214 | 0.82 | 3.0 | 6.0 | 9.0 | 3.2 | 1 | 0 | 0 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 56 | 20 | 0 | 2 | 4 | 5.87 | .358 | 1.67 | 11.8 | 3.3 | 5.4 | 38.1 | 50 | 25 | 25 | 9 | 14 | 23 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 5.97 |