| SP | Maddux, G.Maddux, Greg # >> | 29 | 1995 | R | 89 | 11 | 11 | 7 | 2 | 3.79 | .288 | 1.21 | 9.0 | 1.9 | 6.3 | 76.0 | 76 | 32 | 32 | 8 | 16 | 53 | 2 | 0 | 0 | 0 | 7 | 0 | 2 | 3.61 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 11 | 11 | 3 | 6 | 8.02 | .393 | 1.85 | 12.6 | 4.1 | 3.9 | 55.0 | 77 | 51 | 49 | 7 | 25 | 24 | 0 | 0 | 0 | 0 | 3 | 5 | 1 | 5.42 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 11 | 11 | 4 | 4 | 5.12 | .317 | 1.38 | 9.9 | 2.6 | 4.8 | 70.1 | 77 | 41 | 40 | 8 | 20 | 37 | 2 | 0 | 0 | 0 | 5 | 1 | 1 | 4.33 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 30 | 0 | 2 | 0 | 3.03 | .329 | 1.41 | 8.4 | 4.5 | 9.3 | 32.2 | 30 | 11 | 11 | 1 | 16 | 33 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 3.03 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 27 | 0 | 2 | 1 | 4.05 | .344 | 1.58 | 10.7 | 3.8 | 10.0 | 26.2 | 31 | 12 | 12 | 3 | 11 | 29 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.54 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 18 | 0 | 0 | 1 | 3.24 | .315 | 1.38 | 7.9 | 5.1 | 7.3 | 16.2 | 14 | 9 | 6 | 2 | 9 | 13 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.69 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 28 | 0 | 1 | 1 | 3.72 | .293 | 1.21 | 7.4 | 3.4 | 6.8 | 29.0 | 24 | 12 | 12 | 3 | 11 | 22 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.07 |
| CL | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 26 | 0 | 2 | 3 | 6.66 | .313 | 1.36 | 11.2 | 1.4 | 12.2 | 25.2 | 31 | 20 | 19 | 3 | 4 | 34 | 0 | 13 | 1 | 0 | 0 | 0 | 0 | 2.32 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 87 | 12 | 0 | 0 | 0 | 1.13 | .226 | 0.88 | 6.8 | 1.1 | 6.8 | 16.0 | 12 | 2 | 2 | 0 | 2 | 12 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1.88 |