| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 27 | 27 | 8 | 11 | 3.97 | .304 | 1.30 | 8.5 | 3.2 | 8.1 | 156.1 | 148 | 70 | 69 | 14 | 56 | 141 | 0 | 0 | 0 | 0 | 15 | 1 | 7 | 3.46 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 27 | 27 | 13 | 8 | 3.03 | .273 | 1.10 | 6.3 | 3.7 | 7.4 | 187.1 | 131 | 66 | 63 | 10 | 76 | 153 | 4 | 0 | 0 | 0 | 21 | 4 | 2 | 3.34 |
| SP | Mathewson, C.Mathewson, Christy >> | 29 | 1909 | R | 85 | 26 | 26 | 8 | 6 | 3.41 | .287 | 1.18 | 8.2 | 2.5 | 3.5 | 171.2 | 155 | 70 | 65 | 16 | 48 | 66 | 3 | 0 | 0 | 2 | 17 | 4 | 4 | 4.36 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 76 | 25 | 24 | 8 | 7 | 4.44 | .321 | 1.39 | 7.9 | 4.6 | 7.3 | 154.0 | 136 | 83 | 76 | 24 | 78 | 125 | 1 | 0 | 0 | 1 | 10 | 4 | 2 | 5.00 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 84 | 25 | 25 | 15 | 4 | 3.96 | .287 | 1.17 | 8.0 | 2.7 | 3.6 | 163.2 | 144 | 73 | 72 | 17 | 48 | 65 | 1 | 0 | 0 | 0 | 14 | 6 | 4 | 4.55 |
| RP | Kuo, H.Kuo, Hong-Chih # >> | 29 | 2010 | L | 91 | 58 | 0 | 3 | 4 | 4.21 | .304 | 1.27 | 7.9 | 3.5 | 7.8 | 66.1 | 58 | 31 | 31 | 11 | 26 | 57 | 0 | 6 | 8 | 0 | 0 | 3 | 2 | 4.76 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 44 | 0 | 6 | 3 | 1.94 | .264 | 1.04 | 4.9 | 4.4 | 4.8 | 51.0 | 28 | 11 | 11 | 4 | 25 | 27 | 0 | 9 | 2 | 0 | 0 | 2 | 0 | 4.55 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 78 | 29 | 0 | 5 | 3 | 3.71 | .271 | 1.12 | 6.4 | 3.7 | 6.6 | 34.0 | 24 | 14 | 14 | 1 | 14 | 25 | 0 | 4 | 0 | 0 | 0 | 0 | 2 | 3.15 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 48 | 33 | 0 | 2 | 3 | 3.96 | .299 | 1.25 | 8.6 | 2.6 | 6.0 | 75.0 | 72 | 33 | 33 | 10 | 22 | 50 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 4.36 |