| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 25 | 25 | 8 | 8 | 4.10 | .302 | 1.29 | 9.1 | 2.6 | 11.2 | 162.1 | 163 | 79 | 74 | 23 | 46 | 201 | 0 | 0 | 0 | 0 | 16 | 2 | 1 | 3.25 |
| SP | Gilbert, L.Gilbert, Logan # >> | 28 | 2025 | R | 91 | 25 | 24 | 9 | 10 | 4.41 | .309 | 1.31 | 8.5 | 3.4 | 9.4 | 126.2 | 119 | 65 | 62 | 18 | 47 | 132 | 0 | 0 | 0 | 0 | 9 | 4 | 7 | 3.98 |
| SP | Nelson, R.Nelson, Ryne # >> | 27 | 2025 | R | 81 | 25 | 24 | 7 | 5 | 4.49 | .311 | 1.32 | 9.6 | 2.3 | 9.3 | 112.1 | 119 | 60 | 56 | 22 | 29 | 116 | 0 | 0 | 0 | 0 | 3 | 4 | 1 | 4.37 |
| SP | Kelly, M.Kelly, Merrill >> | 36 | 2025 | R | 74 | 23 | 23 | 12 | 7 | 5.43 | .329 | 1.46 | 10.1 | 3.0 | 7.1 | 131.0 | 147 | 80 | 79 | 20 | 44 | 103 | 1 | 0 | 0 | 1 | 9 | 2 | 1 | 4.47 |
| RP | Bednar, D.Bednar, David >> | 30 | 2025 | R | 78 | 67 | 0 | 5 | 1 | 4.12 | .309 | 1.31 | 8.2 | 3.5 | 10.1 | 59.0 | 54 | 28 | 27 | 6 | 23 | 66 | 0 | 2 | 2 | 0 | 0 | 2 | 1 | 3.36 |
| RP | Estrada, J.Estrada, Jeremiah >> | 26 | 2025 | R | 65 | 45 | 0 | 4 | 2 | 3.26 | .288 | 1.19 | 6.9 | 3.8 | 12.1 | 47.0 | 36 | 17 | 17 | 7 | 20 | 63 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 3.60 |
| SP | Springs, J.Springs, Jeffrey >> | 32 | 2025 | L | 66 | 31 | 0 | 5 | 3 | 5.75 | .346 | 1.57 | 10.5 | 3.6 | 7.9 | 83.0 | 97 | 54 | 53 | 15 | 33 | 73 | 0 | 1 | 2 | 0 | 0 | 2 | 0 | 4.86 |
| SU | Munoz, A.Munoz, Andres >> | 26 | 2025 | R | 91 | 58 | 0 | 0 | 3 | 4.19 | .332 | 1.49 | 7.8 | 5.8 | 9.8 | 53.2 | 46 | 26 | 25 | 4 | 34 | 58 | 0 | 1 | 3 | 0 | 0 | 0 | 6 | 3.72 |