| SP | Leonard, D.Leonard, Dutch † >> | 22 | 1914 | L | 91 | 36 | 36 | 19 | 8 | 2.31 | .249 | 0.98 | 6.1 | 2.7 | 5.5 | 261.0 | 176 | 73 | 67 | 18 | 79 | 159 | 1 | 0 | 0 | 0 | 28 | 5 | 3 | 3.64 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 35 | 35 | 17 | 11 | 3.08 | .266 | 1.08 | 7.9 | 1.8 | 3.9 | 283.0 | 249 | 108 | 97 | 22 | 56 | 124 | 14 | 0 | 0 | 2 | 26 | 2 | 5 | 3.75 |
| SP | Harden, R.Harden, Rich # >> | 27 | 2008 | R | 60 | 33 | 33 | 15 | 9 | 4.79 | .330 | 1.45 | 8.5 | 4.7 | 7.1 | 197.1 | 185 | 111 | 105 | 19 | 102 | 155 | 0 | 0 | 0 | 0 | 18 | 4 | 3 | 4.29 |
| SP | Fernandez, S.Fernandez, Sid # >> | 23 | 1985 | L | 49 | 31 | 31 | 17 | 10 | 3.94 | .292 | 1.21 | 7.1 | 3.9 | 7.7 | 194.1 | 153 | 89 | 85 | 22 | 83 | 165 | 0 | 0 | 0 | 0 | 15 | 4 | 3 | 4.12 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 86 | 0 | 4 | 7 | 3.08 | .280 | 1.13 | 6.6 | 3.5 | 10.4 | 99.1 | 73 | 38 | 34 | 7 | 39 | 114 | 0 | 6 | 5 | 0 | 0 | 4 | 7 | 2.92 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 80 | 0 | 3 | 2 | 3.48 | .302 | 1.28 | 6.2 | 5.5 | 9.0 | 64.2 | 44 | 25 | 25 | 2 | 39 | 64 | 0 | 7 | 1 | 0 | 0 | 1 | 9 | 3.28 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 74 | 0 | 0 | 1 | 6.31 | .344 | 1.57 | 11.6 | 2.6 | 8.3 | 41.1 | 53 | 29 | 29 | 8 | 12 | 38 | 0 | 9 | 3 | 0 | 0 | 0 | 0 | 4.56 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 39 | 11 | 0 | 4 | 1 | 5.77 | .322 | 1.40 | 7.7 | 5.0 | 8.2 | 34.1 | 29 | 23 | 22 | 3 | 19 | 31 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 4.09 |