| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 24 | 24 | 10 | 10 | 4.07 | .332 | 1.46 | 9.2 | 3.9 | 9.1 | 148.1 | 152 | 72 | 67 | 12 | 64 | 149 | 2 | 0 | 0 | 2 | 15 | 5 | 1 | 3.44 |
| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 23 | 23 | 10 | 13 | 3.98 | .284 | 1.17 | 8.7 | 1.9 | 8.6 | 162.2 | 156 | 74 | 72 | 20 | 35 | 154 | 7 | 0 | 0 | 2 | 13 | 3 | 3 | 3.41 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 22 | 22 | 11 | 10 | 4.71 | .317 | 1.36 | 9.5 | 2.8 | 5.7 | 154.2 | 162 | 82 | 81 | 19 | 48 | 98 | 4 | 0 | 0 | 0 | 10 | 5 | 3 | 4.36 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 38 | 0 | 0 | 1 | 3.10 | .304 | 1.31 | 6.8 | 5.0 | 10.6 | 29.0 | 22 | 10 | 10 | 3 | 16 | 34 | 0 | 7 | 1 | 0 | 0 | 0 | 0 | 3.66 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 20 | 0 | 3 | 1 | 4.96 | .319 | 1.35 | 10.1 | 2.3 | 6.2 | 16.1 | 18 | 9 | 9 | 2 | 4 | 11 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.19 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 10 | 0 | 0 | 0 | 5.14 | .382 | 1.86 | 11.6 | 5.1 | 11.6 | 7.0 | 9 | 5 | 4 | 2 | 4 | 9 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 5.86 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 67 | 5 | 0 | 0 | 1 | 4.05 | .333 | 1.50 | 9.0 | 6.0 | 9.0 | 6.2 | 6 | 3 | 3 | 0 | 4 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 37 | 40 | 0 | 1 | 2 | 2.53 | .309 | 1.31 | 7.9 | 3.9 | 6.5 | 32.0 | 28 | 10 | 9 | 3 | 14 | 23 | 0 | 5 | 1 | 0 | 0 | 1 | 0 | 4.19 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 39 | 18 | 0 | 0 | 2 | 4.70 | .301 | 1.26 | 8.5 | 2.9 | 8.7 | 69.0 | 65 | 38 | 36 | 6 | 22 | 67 | 0 | 0 | 1 | 0 | 0 | 2 | 7 | 3.23 |