| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 34 | 34 | 9 | 16 | 4.85 | .339 | 1.51 | 9.5 | 4.1 | 5.3 | 226.1 | 239 | 128 | 122 | 30 | 103 | 134 | 5 | 0 | 0 | 1 | 16 | 6 | 5 | 4.99 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 33 | 33 | 7 | 22 | 5.98 | .337 | 1.51 | 10.1 | 3.5 | 5.1 | 212.1 | 239 | 152 | 141 | 30 | 82 | 120 | 10 | 0 | 0 | 1 | 8 | 3 | 4 | 4.91 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 31 | 31 | 7 | 14 | 5.83 | .353 | 1.62 | 10.7 | 3.9 | 4.8 | 197.2 | 235 | 140 | 128 | 30 | 86 | 104 | 4 | 0 | 0 | 1 | 12 | 2 | 6 | 5.26 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 32 | 32 | 10 | 15 | 5.90 | .363 | 1.67 | 10.4 | 4.6 | 6.0 | 189.0 | 219 | 138 | 124 | 27 | 97 | 127 | 0 | 0 | 0 | 0 | 9 | 7 | 7 | 5.16 |
| SP | Chesbro, J.Chesbro, Jack # >> | 30 | 1904 | R | 65 | 32 | 31 | 15 | 12 | 5.07 | .340 | 1.53 | 10.8 | 2.9 | 5.2 | 215.0 | 259 | 135 | 121 | 23 | 70 | 125 | 10 | 0 | 0 | 1 | 12 | 4 | 7 | 4.26 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 77 | 0 | 4 | 1 | 4.33 | .317 | 1.39 | 7.4 | 5.2 | 7.7 | 104.0 | 85 | 52 | 50 | 12 | 60 | 89 | 0 | 4 | 2 | 0 | 0 | 0 | 1 | 4.52 |
| RP | Papelbon, J.Papelbon, Jonathan # >> | 27 | 2007 | R | 92 | 72 | 0 | 4 | 4 | 4.39 | .311 | 1.31 | 9.0 | 2.8 | 9.3 | 92.1 | 92 | 47 | 45 | 18 | 29 | 95 | 0 | 6 | 3 | 0 | 0 | 4 | 0 | 4.55 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 51 | 0 | 2 | 2 | 4.58 | .368 | 1.67 | 9.8 | 5.2 | 9.8 | 55.0 | 60 | 32 | 28 | 5 | 32 | 60 | 0 | 5 | 2 | 0 | 0 | 4 | 4 | 3.96 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 32 | 0 | 3 | 1 | 6.62 | .342 | 1.53 | 8.5 | 5.4 | 8.7 | 35.1 | 33 | 26 | 26 | 6 | 21 | 34 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 5.17 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 13 | 1 | 2 | 2 | 6.08 | .344 | 1.50 | 9.0 | 4.8 | 7.3 | 26.2 | 26 | 19 | 18 | 4 | 14 | 21 | 0 | 1 | 0 | 0 | 1 | 2 | 1 | 5.23 |