| SP | deGrom, J.deGrom, Jacob # >> | 33 | 2021 | R | 100 | 34 | 34 | 19 | 10 | 3.34 | .282 | 1.15 | 8.3 | 2.1 | 8.8 | 231.2 | 213 | 93 | 86 | 21 | 54 | 227 | 0 | 0 | 0 | 0 | 21 | 6 | 0 | 3.00 |
| SP | Alexander, P.Alexander, Pete # >> | 28 | 1915 | R | 88 | 34 | 34 | 18 | 11 | 3.50 | .286 | 1.18 | 8.3 | 2.3 | 4.3 | 270.0 | 250 | 129 | 105 | 33 | 68 | 129 | 7 | 0 | 0 | 0 | 23 | 6 | 3 | 4.46 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 77 | 88 | 0 | 4 | 2 | 3.39 | .266 | 1.02 | 6.5 | 2.8 | 8.4 | 71.2 | 51 | 27 | 27 | 8 | 22 | 66 | 0 | 3 | 2 | 0 | 0 | 5 | 4 | 3.75 |
| CL | Eckersley, D.Eckersley, Dennis † >> | 36 | 1990 | R | 88 | 55 | 0 | 0 | 1 | 2.10 | .254 | 1.01 | 7.0 | 2.1 | 9.3 | 55.2 | 43 | 13 | 13 | 3 | 13 | 57 | 0 | 47 | 5 | 0 | 0 | 1 | 0 | 2.40 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 43 | 0 | 3 | 3 | 3.74 | .289 | 1.22 | 8.5 | 2.7 | 6.8 | 33.2 | 31 | 22 | 14 | 4 | 10 | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.97 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 15 | 0 | 0 | 1 | 2.87 | .299 | 1.28 | 9.0 | 3.0 | 7.2 | 15.2 | 15 | 5 | 5 | 1 | 5 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.27 |
| RP | Kuo, H.Kuo, Hong-Chih # >> | 29 | 2010 | L | 91 | 59 | 0 | 1 | 1 | 3.80 | .278 | 1.16 | 6.8 | 3.6 | 7.0 | 45.0 | 34 | 21 | 19 | 3 | 18 | 35 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.51 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 29 | 27 | 9 | 12 | 4.81 | .341 | 1.53 | 9.0 | 4.8 | 3.5 | 170.1 | 170 | 96 | 91 | 19 | 90 | 66 | 0 | 0 | 0 | 0 | 16 | 4 | 3 | 5.34 |