| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 31 | 31 | 15 | 6 | 3.88 | .284 | 1.16 | 7.8 | 2.7 | 7.9 | 206.1 | 178 | 89 | 89 | 30 | 61 | 180 | 2 | 0 | 0 | 0 | 18 | 7 | 5 | 4.14 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 30 | 30 | 17 | 6 | 3.01 | .285 | 1.16 | 6.1 | 4.4 | 3.8 | 218.1 | 147 | 78 | 73 | 16 | 107 | 92 | 5 | 0 | 0 | 1 | 19 | 7 | 5 | 4.68 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 29 | 29 | 11 | 12 | 4.76 | .320 | 1.39 | 9.4 | 3.2 | 5.7 | 198.2 | 207 | 107 | 105 | 23 | 70 | 126 | 5 | 0 | 0 | 1 | 14 | 4 | 6 | 4.36 |
| RP | Miller, A.Miller, Andrew >> | 32 | 2017 | L | 86 | 70 | 0 | 4 | 3 | 2.11 | .229 | 0.87 | 4.9 | 3.0 | 7.5 | 42.2 | 23 | 13 | 10 | 4 | 14 | 35 | 0 | 9 | 3 | 0 | 0 | 1 | 1 | 3.64 |
| RP | Marmol, C.Marmol, Carlos # >> | 26 | 2008 | R | 71 | 97 | 0 | 4 | 3 | 3.61 | .280 | 1.15 | 5.0 | 5.4 | 8.8 | 77.1 | 43 | 33 | 31 | 9 | 46 | 75 | 0 | 6 | 4 | 0 | 0 | 1 | 5 | 4.40 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 63 | 71 | 0 | 5 | 1 | 2.90 | .285 | 1.18 | 7.1 | 3.5 | 7.8 | 62.0 | 49 | 21 | 20 | 6 | 24 | 54 | 0 | 7 | 2 | 0 | 0 | 1 | 1 | 3.73 |
| RP | Messersmith, A.Messersmith, Andy † >> | 23 | 1968 | R | 58 | 48 | 0 | 8 | 3 | 2.59 | .247 | 0.98 | 5.2 | 3.7 | 5.3 | 59.0 | 34 | 19 | 17 | 6 | 24 | 35 | 0 | 10 | 2 | 0 | 0 | 0 | 2 | 4.36 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 6 | 0 | 2 | 1 | 4.82 | .333 | 1.50 | 4.0 | 10.0 | 3.0 | 9.1 | 4 | 5 | 5 | 1 | 10 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 7.11 |