| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 29 | 29 | 14 | 6 | 2.48 | .234 | 0.89 | 6.0 | 2.1 | 8.8 | 224.2 | 149 | 64 | 62 | 19 | 52 | 219 | 6 | 0 | 0 | 0 | 22 | 5 | 6 | 2.91 |
| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 28 | 28 | 8 | 11 | 3.53 | .275 | 1.12 | 7.6 | 2.5 | 8.3 | 201.2 | 170 | 86 | 79 | 21 | 55 | 185 | 6 | 0 | 0 | 5 | 16 | 5 | 2 | 3.41 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 27 | 27 | 12 | 11 | 4.36 | .303 | 1.29 | 8.1 | 3.5 | 9.5 | 175.1 | 157 | 93 | 85 | 18 | 69 | 184 | 2 | 0 | 0 | 2 | 17 | 3 | 3 | 3.47 |
| SP | McLain, D.McLain, Denny # >> | 24 | 1968 | R | 79 | 27 | 27 | 9 | 10 | 4.77 | .305 | 1.28 | 9.4 | 2.1 | 6.0 | 183.0 | 192 | 99 | 97 | 39 | 43 | 122 | 8 | 0 | 0 | 0 | 12 | 6 | 0 | 5.24 |
| CL | Gossage, R.Gossage, Rich † >> | 30 | 1981 | R | 90 | 57 | 0 | 5 | 5 | 3.44 | .243 | 0.93 | 5.8 | 2.6 | 7.9 | 65.1 | 42 | 25 | 25 | 9 | 19 | 57 | 0 | 35 | 5 | 0 | 0 | 2 | 1 | 4.02 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 45 | 0 | 3 | 5 | 4.40 | .345 | 1.56 | 9.6 | 4.4 | 4.6 | 43.0 | 46 | 22 | 21 | 6 | 21 | 22 | 0 | 0 | 2 | 0 | 0 | 1 | 1 | 5.33 |
| RP | Fingers, R.Fingers, Rollie >> | 35 | 1981 | R | 54 | 28 | 0 | 3 | 2 | 4.50 | .316 | 1.38 | 8.3 | 4.2 | 5.9 | 26.0 | 24 | 13 | 13 | 7 | 12 | 17 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 6.58 |
| RP | Orosco, J.Orosco, Jesse # >> | 26 | 1983 | L | 25 | 72 | 0 | 1 | 1 | 4.37 | .294 | 1.25 | 7.5 | 3.8 | 5.4 | 47.1 | 39 | 23 | 23 | 7 | 20 | 28 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 5.02 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 51 | 16 | 0 | 0 | 1 | 2.25 | .273 | 1.13 | 7.9 | 2.3 | 6.2 | 16.0 | 14 | 4 | 4 | 1 | 4 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.19 |
| RP | Wetteland, J.Wetteland, John >> | 27 | 1993 | R | 40 | 17 | 0 | 0 | 0 | 6.16 | .329 | 1.47 | 8.5 | 4.7 | 9.5 | 19.0 | 18 | 13 | 13 | 5 | 10 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.89 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 58 | 7 | 0 | 0 | 0 | 7.17 | .326 | 1.45 | 9.9 | 3.4 | 4.3 | 21.1 | 23 | 18 | 17 | 5 | 8 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6.29 |