| SP | Richard, J.Richard, J.R. # >> | 30 | 1980 | R | 90 | 38 | 38 | 19 | 11 | 4.07 | .293 | 1.22 | 7.3 | 3.8 | 8.2 | 234.2 | 189 | 114 | 106 | 22 | 98 | 212 | 1 | 0 | 0 | 1 | 22 | 5 | 2 | 3.73 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 82 | 35 | 35 | 18 | 8 | 3.74 | .294 | 1.22 | 8.7 | 2.3 | 5.7 | 238.1 | 230 | 104 | 99 | 19 | 61 | 150 | 5 | 0 | 0 | 1 | 20 | 7 | 3 | 3.63 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 35 | 34 | 14 | 13 | 4.11 | .303 | 1.28 | 8.4 | 3.2 | 5.3 | 232.1 | 216 | 117 | 106 | 24 | 82 | 137 | 4 | 0 | 0 | 0 | 18 | 5 | 5 | 4.29 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 98 | 0 | 3 | 4 | 4.49 | .330 | 1.46 | 8.8 | 4.3 | 6.1 | 104.1 | 102 | 53 | 52 | 14 | 50 | 70 | 0 | 2 | 4 | 0 | 0 | 2 | 0 | 4.90 |
| RP | Balfour, G.Balfour, Grant # >> | 31 | 2008 | R | 74 | 79 | 0 | 3 | 2 | 5.24 | .307 | 1.32 | 7.8 | 4.1 | 7.2 | 91.0 | 79 | 53 | 53 | 13 | 41 | 73 | 0 | 3 | 0 | 0 | 0 | 1 | 1 | 4.64 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 59 | 0 | 2 | 3 | 4.50 | .302 | 1.30 | 7.8 | 3.9 | 10.5 | 60.0 | 52 | 31 | 30 | 9 | 26 | 70 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 3.92 |
| RP | LaRoche, D.LaRoche, Dave >> | 28 | 1976 | L | 31 | 95 | 0 | 6 | 5 | 4.91 | .328 | 1.43 | 7.4 | 5.5 | 7.6 | 77.0 | 63 | 43 | 42 | 6 | 47 | 65 | 0 | 1 | 2 | 0 | 0 | 3 | 0 | 4.27 |
| CL | Rivera, M.Rivera, Mariano † >> | 39 | 2008 | R | 85 | 92 | 0 | 3 | 5 | 3.83 | .281 | 1.18 | 8.6 | 2.0 | 7.1 | 80.0 | 76 | 36 | 34 | 9 | 18 | 63 | 0 | 49 | 5 | 0 | 0 | 0 | 2 | 3.56 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 42 | 34 | 32 | 14 | 12 | 3.45 | .314 | 1.35 | 7.1 | 5.1 | 4.2 | 237.2 | 188 | 100 | 91 | 19 | 133 | 110 | 2 | 0 | 0 | 0 | 19 | 6 | 4 | 4.87 |