| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 34 | 34 | 10 | 20 | 3.60 | .290 | 1.21 | 9.1 | 1.8 | 8.6 | 264.2 | 268 | 108 | 106 | 32 | 52 | 251 | 10 | 0 | 0 | 0 | 21 | 5 | 6 | 3.32 |
| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 33 | 33 | 11 | 13 | 4.70 | .301 | 1.27 | 8.2 | 3.2 | 8.8 | 226.0 | 207 | 126 | 118 | 34 | 81 | 221 | 4 | 0 | 0 | 2 | 14 | 4 | 7 | 4.13 |
| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 32 | 32 | 6 | 17 | 5.17 | .326 | 1.41 | 9.9 | 2.9 | 8.5 | 203.2 | 223 | 122 | 117 | 26 | 65 | 192 | 0 | 0 | 0 | 0 | 16 | 7 | 3 | 3.84 |
| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 32 | 32 | 11 | 15 | 3.33 | .284 | 1.16 | 8.5 | 1.9 | 5.9 | 245.2 | 232 | 93 | 91 | 24 | 53 | 161 | 10 | 0 | 0 | 4 | 22 | 7 | 2 | 3.69 |
| SP | Adams, B.Adams, Babe # >> | 27 | 1909 | R | 86 | 31 | 31 | 9 | 12 | 5.02 | .317 | 1.35 | 9.5 | 2.8 | 4.8 | 175.2 | 184 | 100 | 98 | 24 | 54 | 94 | 0 | 0 | 0 | 0 | 9 | 7 | 4 | 4.75 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 84 | 0 | 4 | 4 | 3.25 | .286 | 1.18 | 7.8 | 2.9 | 9.2 | 116.1 | 100 | 46 | 42 | 14 | 37 | 118 | 0 | 8 | 5 | 0 | 0 | 3 | 2 | 3.57 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 69 | 0 | 7 | 7 | 4.15 | .304 | 1.26 | 7.2 | 4.3 | 9.0 | 84.2 | 67 | 39 | 39 | 12 | 40 | 84 | 0 | 10 | 7 | 0 | 0 | 4 | 5 | 4.43 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 54 | 0 | 4 | 3 | 2.26 | .298 | 1.28 | 6.1 | 5.6 | 8.5 | 55.2 | 37 | 19 | 14 | 5 | 34 | 52 | 0 | 7 | 1 | 0 | 0 | 0 | 3 | 4.15 |