| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 33 | 33 | 7 | 18 | 5.37 | .338 | 1.51 | 9.9 | 3.7 | 6.0 | 209.2 | 230 | 136 | 125 | 42 | 87 | 139 | 5 | 0 | 0 | 2 | 14 | 4 | 5 | 5.59 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 30 | 30 | 8 | 19 | 5.81 | .350 | 1.59 | 10.7 | 3.7 | 5.7 | 182.2 | 216 | 129 | 118 | 26 | 74 | 115 | 4 | 0 | 0 | 0 | 13 | 5 | 4 | 4.90 |
| RP | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 98 | 0 | 6 | 2 | 3.42 | .301 | 1.28 | 8.5 | 3.1 | 8.8 | 97.1 | 92 | 41 | 37 | 7 | 33 | 95 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 3.03 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 104 | 0 | 4 | 4 | 3.19 | .269 | 1.08 | 6.5 | 3.3 | 8.3 | 149.1 | 108 | 54 | 53 | 13 | 54 | 137 | 0 | 6 | 3 | 0 | 0 | 3 | 0 | 3.44 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 82 | 0 | 5 | 4 | 4.61 | .333 | 1.46 | 8.3 | 4.9 | 8.0 | 84.0 | 77 | 47 | 43 | 6 | 46 | 75 | 0 | 9 | 3 | 0 | 0 | 3 | 3 | 3.89 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 69 | 0 | 4 | 3 | 3.84 | .292 | 1.22 | 7.1 | 4.0 | 7.3 | 70.1 | 55 | 30 | 30 | 5 | 31 | 57 | 0 | 5 | 2 | 0 | 0 | 1 | 2 | 3.67 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 55 | 0 | 5 | 1 | 2.41 | .297 | 1.25 | 7.1 | 4.2 | 7.2 | 71.0 | 56 | 24 | 19 | 7 | 33 | 57 | 0 | 2 | 1 | 0 | 0 | 1 | 2 | 4.11 |