| SP | Neagle, D.Neagle, Denny >> | 32 | 1997 | L | 71 | 32 | 32 | 8 | 13 | 4.70 | .302 | 1.29 | 9.0 | 2.7 | 5.7 | 199.1 | 199 | 107 | 104 | 30 | 59 | 126 | 2 | 0 | 0 | 1 | 0 | 1 | 1 | 4.60 |
| SP | Darvish, Y.Darvish, Yu >> | 21 | 2013 | R | 75 | 31 | 31 | 6 | 14 | 2.44 | .268 | 1.07 | 6.5 | 3.2 | 8.2 | 224.2 | 162 | 77 | 61 | 24 | 79 | 203 | 4 | 0 | 0 | 0 | 0 | 6 | 7 | 3.72 |
| SP | Strasburg, S.Strasburg, Stephen >> | 23 | 2010 | R | 69 | 30 | 30 | 10 | 12 | 3.82 | .263 | 1.05 | 7.8 | 1.7 | 7.9 | 167.1 | 144 | 76 | 71 | 21 | 31 | 146 | 1 | 0 | 0 | 1 | 0 | 4 | 1 | 3.51 |
| SP | Rogers, K.Rogers, Kenny >> | 33 | 1998 | L | 61 | 30 | 30 | 5 | 17 | 5.41 | .308 | 1.34 | 9.8 | 2.3 | 5.5 | 188.0 | 204 | 119 | 113 | 31 | 47 | 114 | 2 | 0 | 0 | 1 | 0 | 0 | 3 | 4.68 |
| SP | Zimmermann, J.Zimmermann, Jordan >> | 23 | 2011 | R | 23 | 27 | 27 | 7 | 12 | 5.26 | .318 | 1.39 | 10.2 | 2.3 | 5.5 | 142.0 | 161 | 87 | 83 | 25 | 37 | 87 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 4.87 |
| RP | Guardado, E.Guardado, Eddie >> | 32 | 2003 | L | 47 | 79 | 0 | 4 | 3 | 2.53 | .256 | 1.01 | 6.8 | 2.3 | 7.6 | 142.1 | 108 | 40 | 40 | 16 | 36 | 120 | 0 | 3 | 3 | 0 | 0 | 3 | 3 | 3.60 |
| RP | Martinez, R.Martinez, Ramon >> | 34 | 1990 | R | 54 | 63 | 0 | 7 | 2 | 2.00 | .199 | 0.73 | 5.2 | 1.4 | 5.8 | 117.0 | 67 | 26 | 26 | 12 | 18 | 76 | 0 | 1 | 0 | 0 | 0 | 2 | 3 | 3.55 |
| RP | Williamson, S.Williamson, Scott >> | 30 | 1999 | R | 73 | 39 | 0 | 3 | 3 | 1.41 | .193 | 0.72 | 4.1 | 2.5 | 6.8 | 44.2 | 20 | 8 | 7 | 5 | 12 | 33 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 3.80 |
| RP | Street, H.Street, Huston >> | 26 | 2005 | R | 77 | 19 | 0 | 3 | 1 | 2.03 | .216 | 0.83 | 4.5 | 3.1 | 8.0 | 26.2 | 13 | 7 | 6 | 4 | 9 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.27 |
| SU | Williams, M.Williams, Mitch >> | 33 | 1989 | L | 45 | 31 | 0 | 1 | 0 | 2.41 | .211 | 0.80 | 4.9 | 2.5 | 9.0 | 33.2 | 18 | 9 | 9 | 4 | 9 | 33 | 0 | 7 | 5 | 0 | 0 | 0 | 1 | 3.39 |