| SP | Johnson, R.Johnson, Randy † $ >> | 41 | 2004 | L | 90 | 28 | 28 | 13 | 8 | 3.44 | .273 | 1.11 | 8.1 | 1.9 | 9.0 | 209.1 | 187 | 81 | 80 | 31 | 45 | 210 | 5 | 0 | 0 | 1 | 18 | 4 | 1 | 3.62 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 78 | 27 | 27 | 10 | 9 | 4.77 | .326 | 1.43 | 9.5 | 3.5 | 10.1 | 179.1 | 188 | 99 | 95 | 30 | 69 | 201 | 0 | 0 | 0 | 0 | 14 | 3 | 4 | 4.14 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 72 | 27 | 26 | 5 | 14 | 5.44 | .324 | 1.42 | 9.6 | 3.3 | 6.7 | 152.1 | 162 | 99 | 92 | 46 | 55 | 113 | 0 | 0 | 0 | 0 | 12 | 2 | 5 | 6.57 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 77 | 0 | 5 | 6 | 2.99 | .261 | 1.04 | 5.9 | 3.6 | 8.6 | 126.1 | 82 | 43 | 42 | 14 | 50 | 121 | 0 | 10 | 3 | 0 | 0 | 2 | 0 | 3.76 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 82 | 71 | 0 | 4 | 5 | 2.90 | .288 | 1.19 | 6.0 | 4.8 | 11.6 | 80.2 | 53 | 27 | 26 | 8 | 43 | 103 | 0 | 3 | 4 | 0 | 0 | 2 | 8 | 3.41 |
| RP | Rodney, F.Rodney, Fernando >> | 35 | 2012 | R | 79 | 57 | 0 | 2 | 6 | 3.99 | .295 | 1.24 | 8.2 | 3.0 | 8.9 | 70.0 | 64 | 31 | 31 | 4 | 23 | 69 | 0 | 8 | 4 | 0 | 0 | 1 | 2 | 2.80 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 73 | 36 | 0 | 1 | 1 | 3.72 | .270 | 1.11 | 6.3 | 3.7 | 11.0 | 46.0 | 32 | 19 | 19 | 6 | 19 | 56 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 3.50 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 72 | 34 | 0 | 2 | 4 | 3.60 | .281 | 1.18 | 8.1 | 2.5 | 8.8 | 40.0 | 36 | 16 | 16 | 5 | 11 | 39 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 3.50 |