| SP | Greinke, Z.Greinke, Zack $ >> | 32 | 2015 | R | 93 | 33 | 33 | 13 | 11 | 4.36 | .290 | 1.20 | 8.3 | 2.5 | 7.5 | 231.0 | 214 | 112 | 112 | 44 | 64 | 193 | 3 | 0 | 0 | 0 | 17 | 5 | 1 | 4.70 |
| SP | Hunter, C.Hunter, Catfish $ >> | 26 | 1972 | R | 84 | 32 | 32 | 6 | 18 | 5.30 | .341 | 1.54 | 9.9 | 3.9 | 5.8 | 217.1 | 239 | 135 | 128 | 34 | 95 | 141 | 3 | 0 | 0 | 0 | 11 | 3 | 2 | 5.09 |
| SP | Ryan, N.Ryan, Nolan $$ >> | 44 | 1991 | R | 79 | 32 | 32 | 12 | 9 | 3.91 | .308 | 1.31 | 7.3 | 4.5 | 9.3 | 200.1 | 162 | 89 | 87 | 24 | 101 | 206 | 0 | 0 | 0 | 0 | 19 | 5 | 9 | 4.09 |
| SP | Higuera, T.Higuera, Teddy >> | 30 | 1988 | L | 63 | 32 | 32 | 13 | 14 | 4.51 | .318 | 1.35 | 8.2 | 4.0 | 6.5 | 215.1 | 195 | 112 | 108 | 33 | 95 | 156 | 4 | 0 | 0 | 0 | 17 | 11 | 0 | 5.02 |
| SP | Maddux, G.Maddux, Greg $$ >> | 29 | 1995 | R | 90 | 19 | 2 | 4 | 4 | 4.54 | .247 | 0.98 | 7.6 | 1.4 | 8.3 | 39.2 | 33 | 20 | 20 | 5 | 6 | 36 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 3.28 |
| CL | Street, H.Street, Huston † $ >> | 29 | 2012 | R | 95 | 64 | 0 | 5 | 4 | 2.90 | .270 | 1.11 | 6.6 | 3.4 | 9.0 | 71.1 | 52 | 23 | 23 | 10 | 27 | 71 | 0 | 32 | 4 | 0 | 0 | 0 | 1 | 3.97 |
| SU | Hochevar, L.Hochevar, Luke # >> | 30 | 2013 | R | 74 | 65 | 0 | 2 | 3 | 4.77 | .334 | 1.47 | 9.5 | 3.8 | 9.8 | 71.2 | 75 | 43 | 38 | 9 | 30 | 77 | 0 | 6 | 9 | 0 | 0 | 3 | 2 | 3.87 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 71 | 84 | 0 | 5 | 3 | 4.60 | .324 | 1.39 | 8.9 | 3.7 | 9.6 | 101.2 | 100 | 55 | 52 | 25 | 41 | 108 | 0 | 5 | 0 | 0 | 0 | 5 | 0 | 5.45 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 67 | 65 | 0 | 4 | 0 | 1.23 | .248 | 0.96 | 4.7 | 4.0 | 6.0 | 65.2 | 34 | 11 | 9 | 3 | 29 | 43 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 3.71 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 66 | 47 | 0 | 3 | 3 | 3.63 | .316 | 1.35 | 6.6 | 5.5 | 10.6 | 52.0 | 38 | 21 | 21 | 6 | 32 | 61 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 4.12 |
| SP | Beckett, J.Beckett, Josh >> | 31 | 2011 | R | 56 | 28 | 28 | 7 | 16 | 5.90 | .354 | 1.61 | 9.5 | 4.9 | 7.2 | 166.1 | 176 | 119 | 109 | 40 | 91 | 132 | 0 | 0 | 0 | 0 | 10 | 6 | 3 | 6.30 |