| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 33 | 33 | 17 | 12 | 3.90 | .301 | 1.28 | 8.4 | 3.1 | 8.3 | 226.1 | 212 | 99 | 98 | 21 | 77 | 208 | 6 | 0 | 0 | 1 | 18 | 3 | 4 | 3.43 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 75 | 32 | 32 | 10 | 10 | 4.47 | .325 | 1.42 | 9.0 | 3.8 | 6.9 | 239.1 | 239 | 122 | 119 | 30 | 102 | 184 | 5 | 0 | 0 | 2 | 11 | 5 | 8 | 4.44 |
| SP | Schilling, C.Schilling, Curt # >> | 36 | 2002 | R | 65 | 30 | 30 | 16 | 6 | 4.56 | .292 | 1.21 | 8.7 | 2.2 | 9.0 | 211.1 | 204 | 108 | 107 | 32 | 51 | 211 | 2 | 0 | 0 | 0 | 16 | 7 | 3 | 3.80 |
| RP | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 89 | 0 | 13 | 4 | 1.94 | .245 | 0.96 | 4.9 | 3.7 | 11.5 | 116.0 | 63 | 26 | 25 | 10 | 48 | 148 | 0 | 10 | 3 | 0 | 0 | 2 | 9 | 2.86 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 68 | 0 | 4 | 6 | 1.94 | .247 | 0.96 | 5.6 | 3.1 | 9.3 | 88.1 | 55 | 19 | 19 | 2 | 30 | 91 | 0 | 14 | 0 | 0 | 0 | 2 | 7 | 2.32 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 86 | 43 | 0 | 5 | 2 | 3.42 | .272 | 1.08 | 7.9 | 1.8 | 6.5 | 50.0 | 44 | 20 | 19 | 7 | 10 | 36 | 0 | 7 | 2 | 0 | 0 | 2 | 0 | 4.10 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 27 | 0 | 2 | 1 | 2.54 | .248 | 0.99 | 7.7 | 1.3 | 10.3 | 28.1 | 24 | 9 | 8 | 1 | 4 | 32 | 0 | 5 | 0 | 0 | 0 | 0 | 1 | 1.61 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 76 | 17 | 0 | 0 | 0 | 3.32 | .260 | 1.05 | 7.1 | 2.4 | 9.0 | 19.0 | 15 | 7 | 7 | 1 | 5 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.47 |