| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 20 | 20 | 8 | 8 | 5.87 | .339 | 1.51 | 10.0 | 3.7 | 8.5 | 122.2 | 135 | 81 | 80 | 21 | 50 | 115 | 0 | 0 | 0 | 0 | 7 | 4 | 2 | 4.68 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 19 | 19 | 5 | 11 | 5.86 | .351 | 1.59 | 10.5 | 3.9 | 5.7 | 116.2 | 135 | 77 | 76 | 15 | 50 | 73 | 2 | 0 | 0 | 0 | 7 | 4 | 1 | 4.82 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 71 | 19 | 19 | 5 | 12 | 5.43 | .318 | 1.40 | 9.0 | 3.6 | 5.1 | 114.1 | 114 | 75 | 69 | 16 | 46 | 65 | 1 | 0 | 0 | 1 | 8 | 0 | 0 | 4.89 |
| SP | Tudor, J.Tudor, John # >> | 31 | 1985 | L | 63 | 19 | 19 | 9 | 6 | 3.98 | .286 | 1.20 | 8.5 | 2.4 | 4.4 | 133.1 | 125 | 63 | 59 | 15 | 35 | 65 | 4 | 0 | 0 | 1 | 12 | 0 | 2 | 4.28 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 19 | 19 | 2 | 10 | 6.80 | .388 | 1.88 | 10.8 | 6.2 | 9.1 | 99.1 | 119 | 78 | 75 | 18 | 68 | 100 | 0 | 0 | 0 | 0 | 7 | 2 | 1 | 5.46 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 52 | 0 | 2 | 4 | 2.84 | .303 | 1.28 | 8.1 | 3.5 | 9.5 | 69.2 | 62 | 22 | 22 | 7 | 27 | 73 | 0 | 5 | 2 | 0 | 0 | 2 | 2 | 3.46 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 70 | 47 | 0 | 2 | 1 | 2.31 | .271 | 1.08 | 6.2 | 3.6 | 8.2 | 58.1 | 40 | 16 | 15 | 5 | 23 | 53 | 0 | 8 | 1 | 0 | 0 | 2 | 5 | 3.59 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 5 | 0 | 0 | 0 | 6.35 | .376 | 1.72 | 10.6 | 5.3 | 6.5 | 22.2 | 26 | 17 | 16 | 6 | 13 | 16 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 7.14 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 52 | 20 | 0 | 3 | 2 | 7.30 | .384 | 1.87 | 13.3 | 3.8 | 5.9 | 40.2 | 59 | 33 | 33 | 8 | 17 | 26 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 5.58 |