| SP | deGrom, J.deGrom, Jacob $$ >> | 33 | 2021 | R | 100 | 33 | 33 | 17 | 7 | 3.02 | .256 | 1.01 | 6.9 | 2.2 | 9.0 | 217.1 | 166 | 74 | 73 | 22 | 54 | 218 | 0 | 0 | 0 | 0 | 23 | 4 | 0 | 3.11 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 32 | 32 | 15 | 13 | 3.96 | .299 | 1.27 | 8.7 | 2.8 | 8.0 | 209.1 | 202 | 97 | 92 | 21 | 64 | 186 | 3 | 0 | 0 | 0 | 18 | 2 | 2 | 3.47 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 31 | 31 | 7 | 12 | 3.77 | .299 | 1.27 | 8.2 | 3.2 | 7.8 | 186.1 | 170 | 87 | 78 | 22 | 67 | 161 | 1 | 0 | 0 | 0 | 22 | 2 | 5 | 3.92 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 31 | 31 | 13 | 9 | 4.81 | .329 | 1.44 | 9.6 | 3.4 | 4.7 | 183.1 | 195 | 106 | 98 | 20 | 69 | 95 | 2 | 0 | 0 | 0 | 14 | 6 | 1 | 4.61 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 68 | 0 | 6 | 2 | 2.64 | .241 | 0.94 | 5.4 | 3.1 | 9.6 | 81.2 | 49 | 25 | 24 | 7 | 28 | 86 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 3.07 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 55 | 0 | 2 | 1 | 4.38 | .299 | 1.28 | 7.5 | 4.0 | 7.3 | 49.1 | 41 | 24 | 24 | 7 | 22 | 40 | 0 | 3 | 0 | 0 | 0 | 0 | 2 | 4.57 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 11 | 0 | 2 | 2 | 5.33 | .372 | 1.78 | 11.9 | 4.3 | 5.0 | 25.1 | 33 | 16 | 15 | 4 | 12 | 14 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 5.40 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 19 | 0 | 0 | 3 | 4.87 | .324 | 1.43 | 8.4 | 4.4 | 5.1 | 81.1 | 76 | 52 | 44 | 5 | 40 | 46 | 0 | 1 | 0 | 0 | 0 | 1 | 7 | 4.19 |