| SP | Walsh, E.Walsh, Ed † $$ >> | 29 | 1910 | R | 93 | 33 | 33 | 16 | 12 | 3.91 | .302 | 1.28 | 8.8 | 2.8 | 4.8 | 223.1 | 217 | 102 | 97 | 24 | 69 | 120 | 9 | 0 | 0 | 3 | 17 | 4 | 5 | 4.30 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 32 | 32 | 11 | 10 | 4.33 | .314 | 1.35 | 9.3 | 2.9 | 3.9 | 210.0 | 216 | 106 | 101 | 21 | 68 | 91 | 1 | 0 | 0 | 0 | 15 | 5 | 5 | 4.48 |
| SP | Reulbach, E.Reulbach, Ed $ >> | 24 | 1906 | R | 60 | 32 | 32 | 9 | 15 | 4.75 | .327 | 1.44 | 8.0 | 4.9 | 3.3 | 195.0 | 173 | 104 | 103 | 14 | 107 | 72 | 1 | 0 | 0 | 1 | 14 | 4 | 5 | 4.90 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 28 | 28 | 11 | 8 | 4.07 | .288 | 1.21 | 8.1 | 2.8 | 5.1 | 196.2 | 176 | 97 | 89 | 28 | 61 | 112 | 8 | 0 | 0 | 1 | 16 | 2 | 3 | 4.68 |
| CL | Chapman, A.Chapman, Aroldis † >> | 26 | 2014 | L | 94 | 62 | 0 | 4 | 9 | 2.63 | .280 | 1.14 | 4.7 | 5.5 | 10.8 | 65.0 | 34 | 19 | 19 | 3 | 40 | 78 | 0 | 37 | 2 | 0 | 0 | 2 | 3 | 3.14 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 75 | 0 | 6 | 2 | 1.80 | .254 | 0.97 | 6.8 | 1.9 | 6.7 | 90.0 | 68 | 20 | 18 | 8 | 19 | 67 | 0 | 2 | 3 | 0 | 0 | 5 | 2 | 3.47 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 49 | 0 | 4 | 2 | 3.65 | .328 | 1.45 | 7.2 | 5.9 | 9.3 | 56.2 | 45 | 23 | 23 | 3 | 37 | 58 | 0 | 3 | 0 | 0 | 0 | 1 | 1 | 3.66 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 63 | 31 | 0 | 0 | 2 | 3.34 | .321 | 1.35 | 9.0 | 3.4 | 11.2 | 29.2 | 29 | 14 | 11 | 2 | 11 | 36 | 0 | 1 | 2 | 0 | 0 | 2 | 1 | 2.76 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 55 | 14 | 0 | 2 | 2 | 5.02 | .295 | 1.26 | 9.0 | 2.6 | 7.1 | 14.1 | 14 | 9 | 8 | 3 | 4 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 5.07 |
| RP | Radatz, D.Radatz, Dick >> | 26 | 1963 | R | 20 | 21 | 0 | 1 | 0 | 1.72 | .217 | 0.83 | 4.1 | 3.5 | 7.3 | 31.1 | 14 | 6 | 6 | 3 | 12 | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.81 |
| RP | Quisenberry, D.Quisenberry, Dan # >> | 30 | 1983 | R | 29 | 32 | 0 | 5 | 1 | 4.32 | .284 | 1.16 | 8.6 | 1.8 | 3.9 | 73.0 | 70 | 35 | 35 | 10 | 15 | 32 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.60 |