| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 25 | 25 | 10 | 10 | 4.28 | .298 | 1.24 | 8.6 | 2.6 | 9.1 | 172.1 | 164 | 91 | 82 | 23 | 50 | 174 | 1 | 0 | 0 | 0 | 12 | 5 | 3 | 3.67 |
| SP | Adams, B.Adams, Babe # >> | 27 | 1909 | R | 86 | 24 | 24 | 12 | 8 | 4.31 | .322 | 1.40 | 9.9 | 2.8 | 5.1 | 135.2 | 148 | 69 | 65 | 12 | 42 | 77 | 0 | 0 | 0 | 0 | 10 | 3 | 4 | 4.01 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 84 | 24 | 24 | 6 | 9 | 4.49 | .334 | 1.49 | 10.8 | 2.6 | 5.0 | 126.1 | 151 | 66 | 63 | 25 | 37 | 70 | 0 | 0 | 0 | 0 | 5 | 2 | 3 | 5.40 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 23 | 23 | 12 | 8 | 5.21 | .331 | 1.47 | 10.7 | 2.5 | 7.3 | 160.2 | 191 | 101 | 93 | 37 | 45 | 130 | 3 | 0 | 0 | 0 | 11 | 3 | 1 | 5.28 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 64 | 0 | 1 | 3 | 2.93 | .241 | 0.93 | 6.4 | 2.0 | 8.4 | 95.1 | 68 | 34 | 31 | 8 | 21 | 89 | 0 | 6 | 3 | 0 | 0 | 2 | 1 | 2.95 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 41 | 0 | 1 | 2 | 3.97 | .306 | 1.24 | 6.1 | 5.2 | 9.8 | 47.2 | 32 | 23 | 21 | 6 | 27 | 51 | 0 | 7 | 0 | 0 | 0 | 4 | 1 | 4.47 |
| RP | Russell, J.Russell, Jeff # >> | 28 | 1989 | R | 56 | 33 | 0 | 0 | 2 | 6.03 | .364 | 1.69 | 11.1 | 4.2 | 7.7 | 34.1 | 42 | 26 | 23 | 4 | 16 | 29 | 0 | 0 | 2 | 0 | 0 | 1 | 1 | 4.32 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 56 | 2 | 0 | 0 | 1 | 27.00 | .600 | 4.50 | - | - | - | 0.2 | 2 | 2 | 2 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | - |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 9 | 0 | 1 | 2 | 4.19 | .348 | 1.55 | 9.9 | 4.3 | 5.7 | 19.1 | 21 | 10 | 9 | 2 | 9 | 12 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.68 |