| SP | Skubal, T.Skubal, Tarik $ >> | 28 | 2025 | L | 100 | 25 | 25 | 9 | 13 | 3.80 | .279 | 1.11 | 8.0 | 2.0 | 10.3 | 168.1 | 149 | 74 | 71 | 20 | 38 | 192 | 2 | 0 | 0 | 1 | 15 | 8 | 1 | 3.08 |
| SP | Rasmussen, D.Rasmussen, Drew >> | 29 | 2025 | R | 85 | 24 | 24 | 9 | 7 | 5.43 | .320 | 1.36 | 9.5 | 2.7 | 7.1 | 121.0 | 128 | 73 | 73 | 22 | 36 | 95 | 0 | 0 | 0 | 0 | 4 | 7 | 2 | 4.86 |
| SP | Sanchez, C.Sanchez, Cristopher $$ >> | 28 | 2025 | L | 82 | 23 | 23 | 10 | 7 | 4.80 | .341 | 1.55 | 11.4 | 2.6 | 8.5 | 137.0 | 173 | 75 | 73 | 22 | 39 | 130 | 0 | 0 | 0 | 0 | 14 | 1 | 2 | 4.07 |
| SP | Luzardo, J.Luzardo, Jesus >> | 27 | 2025 | L | 68 | 24 | 24 | 10 | 7 | 4.73 | .334 | 1.48 | 9.7 | 3.7 | 10.0 | 137.0 | 147 | 72 | 72 | 13 | 56 | 152 | 1 | 0 | 0 | 0 | 9 | 3 | 3 | 3.31 |
| SP | Valdez, F.Valdez, Framber >> | 31 | 2025 | L | 64 | 23 | 22 | 7 | 11 | 6.02 | .355 | 1.60 | 10.8 | 3.7 | 7.1 | 133.0 | 159 | 89 | 89 | 23 | 54 | 105 | 0 | 1 | 0 | 0 | 10 | 7 | 8 | 5.05 |
| RP | Bednar, D.Bednar, David >> | 30 | 2025 | R | 80 | 72 | 0 | 1 | 0 | 3.95 | .307 | 1.32 | 8.4 | 3.5 | 10.7 | 79.2 | 74 | 38 | 35 | 8 | 31 | 94 | 0 | 1 | 1 | 0 | 0 | 1 | 4 | 3.15 |
| CL | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 100 | 52 | 0 | 5 | 4 | 4.02 | .315 | 1.36 | 7.5 | 4.9 | 10.0 | 53.2 | 44 | 25 | 24 | 4 | 29 | 59 | 0 | 22 | 3 | 0 | 0 | 1 | 5 | 3.45 |
| RP | Bender, A.Bender, Anthony >> | 30 | 2025 | R | 76 | 61 | 0 | 3 | 2 | 4.82 | .294 | 1.22 | 8.9 | 2.2 | 7.8 | 61.2 | 60 | 33 | 33 | 10 | 15 | 53 | 0 | 1 | 1 | 0 | 0 | 2 | 1 | 4.23 |
| RP | Banks, T.Banks, Tanner >> | 33 | 2025 | L | 68 | 77 | 0 | 3 | 2 | 4.37 | .311 | 1.29 | 9.1 | 2.5 | 6.9 | 68.0 | 69 | 33 | 33 | 10 | 19 | 52 | 0 | 0 | 2 | 0 | 0 | 4 | 1 | 4.40 |
| SP | Strider, S.Strider, Spencer >> | 26 | 2025 | R | 26 | 20 | 2 | 5 | 2 | 3.76 | .315 | 1.38 | 8.3 | 4.3 | 6.9 | 38.1 | 35 | 16 | 16 | 4 | 18 | 29 | 0 | 2 | 0 | 0 | 1 | 0 | 1 | 4.26 |